Application of the SMILE-Derived Glued Lenticule Patch Graft in Microperforations and Partial-Thickness Corneal Defects

Cornea
Vipul BhandariRahul Pandey

Abstract

To report the initial clinical outcomes of the small incision lenticule extraction (SMILE)-derived glued lenticule patch graft for management of microperforations and complicated corneal tears. In this single-center case series, 7 eyes (of 7 patients) that presented with microperforations, partial-thickness corneal defect, and traumatic complicated corneal tear were repaired with a lenticule patch graft obtained from Refractive Lenticule Extraction (ReLEx) with the SMILE procedure. The patch was secured to the recipient eye using fibrin glue. Preoperatively, anterior segment optical coherence tomography was used to assess the depth of the defect and to decide the thickness of the lenticule. Patients were followed up on days 1, 7, and 15 and at 1 and 3 months postoperatively. Main outcome parameters measured were best-corrected visual acuity, clarity of the graft, and restoration of optical and tectonic integrity. All surgeries were uneventful. Significant improvement in visual acuity was seen from 15 days onward in 5 of 7 eyes. The lenticule graft was well apposed and remained clear until the last follow-up visit in all eyes treated. The patch graft from the SMILE-derived lenticule using fibrin glue seems to serve as a safe, fe...Continue Reading

References

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Citations

Apr 21, 2016·Current Opinion in Ophthalmology·Sonal Tuli, Matthew Gray
Mar 16, 2018·Vestnik oftalmologii·E N Eskina, K K Davtyan
Apr 17, 2018·The Journal of International Medical Research·Om Prakash PantCheng-Wei Lu
Dec 29, 2017·Indian Journal of Ophthalmology·Sri GaneshRaghavender Reddy Arra
Aug 9, 2018·The Journal of International Medical Research·Om Prakash PantCheng-Wei Lu
Nov 23, 2019·International Ophthalmology·Hong YangQin Jiang
Apr 15, 2017·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Mohamed Samy Abd ElazizAbdel Rahman El SaebaySarhan
Dec 21, 2019·Indian Journal of Ophthalmology·Rashmi DeshmukhRasik Vajpayee
Dec 21, 2020·Journal of Cellular and Molecular Medicine·Shenyang LiJiansu Chen
Jan 13, 2021·Journal of Refractive Surgery·Yanfeng ShangFengju Zhang
Sep 8, 2019·Progress in Retinal and Eye Research·Andri K RiauJodhbir S Mehta
Sep 1, 2020·Survey of Ophthalmology·Deepali SinghalJeewan S Titiyal
Jun 16, 2021·Tissue Engineering. Part a·Andri K RiauJodhbir S Mehta

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