Application of the world health organization criteria to predict radiographic pneumonia in a US-based pediatric emergency department

The Pediatric Infectious Disease Journal
Sarah L WingerterMark I Neuman

Abstract

The World Health Organization (WHO) established guidelines that rely on simple clinical signs for the diagnosis of childhood pneumonia in resource-limited settings. Our objective was to evaluate the test characteristics of the WHO criteria for the diagnosis of radiographic pneumonia in the emergency department setting. We prospectively collected clinical information from children ≤5 years of age presenting to a US-based pediatric emergency department who had a chest radiograph performed for suspicion of pneumonia. Patients were classified as meeting the WHO case definition of pneumonia if they had both 1) cough or difficulty breathing and 2) age-specific WHO-defined tachypnea. The primary outcome was radiographic pneumonia based on the final radiology report. Among children with cough or with difficulty breathing, receiver operator characteristic curve analysis was used to evaluate the test characteristics of triage respiratory rate, temperature and oxygen saturation for the diagnosis of radiographic pneumonia. Two thousand eight children were enrolled. Median age was 19 months, and 28.5% had tachypnea based upon age-specific respiratory rate thresholds. Of the 324 children with radiographic pneumonia, 111 met the WHO case defi...Continue Reading

References

Mar 6, 1993·BMJ : British Medical Journal·F E OnyangoJ Kitonyi
Mar 15, 2002·The Lancet Infectious Diseases·Brian G WilliamsChristopher Dye
Oct 4, 2006·Pediatrics·Anne Merewood
Sep 2, 2008·Indian Journal of Pediatrics·M R Savitha, Jagadish B Khanagavi
Jul 1, 2009·Pediatrics·Bonnie MathewsMark I Neuman
Dec 25, 2009·The Pediatric Infectious Disease Journal·Sonal ShahMark I Neuman
May 27, 2010·JAMA : the Journal of the American Medical Association·James A BerkleyD James Nokes
Sep 28, 2010·Archives of Disease in Childhood·Maria-Regina A CardosoSimon N Cousens
Jul 13, 2011·Pediatrics·Mark I NeumanRichard G Bachur

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Citations

Jan 28, 2014·The Lancet. Respiratory Medicine·Rasa IzadnegahdarShamim A Qazi
Oct 27, 2012·The Pediatric Infectious Disease Journal·Shabir A MadhiJoanne Wolter
Jan 29, 2013·Indian Journal of Public Health·Sunil BhatnagarOm P Gupta
Dec 1, 2012·Journal of the Pediatric Infectious Diseases Society·Derek J Williams, Samir S Shah
Sep 17, 2013·Pediatric Pulmonology·Fernando A TorresFernando Ferrero
May 16, 2015·Indian Journal of Pediatrics·Qiang Qin, Kun-ling Shen
Mar 15, 2015·The Lancet Infectious Diseases·Clotilde Rambaud-AlthausValérie D'Acremont
Dec 15, 2017·Journal of Clinical Microbiology·C M C Rodrigues, H Groves
Oct 17, 2019·Thorax·Peter P Moschovis, Patricia L Hibberd
Oct 22, 2013·The Pediatric Infectious Disease Journal·Cristiana M Nascimento-CarvalhoKatherine L O'Brien
Nov 17, 2015·The Pediatric Infectious Disease Journal·Matthew S KellySamir S Shah
Mar 17, 2020·The Pediatric Infectious Disease Journal·Hila GavrieliDavid Greenberg
Jan 15, 2014·The Pediatric Infectious Disease Journal·Cristiana M Nascimento-CarvalhoKatherine L O'Brien
Mar 24, 2017·World Journal of Pediatrics : WJP·Keegan Kosasih, Udantha Abeyratne
Mar 11, 2017·European Journal of Pediatrics·Are Stuwitz BergBritt Nakstad
Jun 23, 2018·Journal of Ultrasound·Daniele OrsoNicola Guglielmo
Apr 9, 2019·The European Respiratory Journal·Phuong T K NguyenBen J Marais
Dec 1, 2014·Pneumonia·Kerry-Ann F O'GradyAnne B Chang

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