PMID: 9549340Apr 29, 1998Paper

Application of ultrasound energy as a new drug delivery system

Nihon rinsho. Japanese journal of clinical medicine
Katsuro Tachibana, S Tachibana

Abstract

Ultrasound is frequently used in medicine for diagnostic purposes. Recently, there have been numerous reports on application of ultrasound energy for controlling drug release or targeting. This new concept of therapeutic ultrasound combined with drugs has induced excitement in various areas. Ultrasound energy can enhance effects of thrombolytic agents as urokinase. Ultrasound emitting catheters are currently being developed for cardiovascular diseases. Device with ultrasound transducers implanted in transdermal drug patches are also being evaluated for possible delivery of insulin through the skin. Chemical activation of drugs by ultrasound energy for treatment of cancers is another new field recently termed as "Sonodynamic Therapy". Various examples of application of ultrasound for drug delivery systems are discussed.

Citations

Apr 25, 2008·Ultrasonics·Katsuro TachibanaYurika Ikeda-Dantsuji
May 20, 2008·Advanced Drug Delivery Reviews·Ghaleb A Husseini, William G Pitt
Jun 25, 2009·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·Hironobu MaedaTatsuji Nishihara
Mar 20, 2004·Ultrasonics Sonochemistry·Tinghe YuTimothy J Mason

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