Application of Vestibular Spontaneous Response as a Diagnostic Aid for Meniere's Disease

Annals of Biomedical Engineering
Zeinab A DastgheibZ Moussavi

Abstract

In this paper, we report on a new method for assisting in Meniere's disease diagnosis. An accurate diagnosis of Meniere's is challenging, and requires an expert opinion after observing several clinical assessments and tests over a period of time. Our proposed method is based on the analysis of the spontaneous and driven ear evoked responses recorded using Electrovestibulography (EVestG). We used the EVestG signals of 35 individuals suspected of Meniere's and 26 age-matched healthy controls, out of which data of 14 patients with Meniere's and 16 healthy controls were used for developing the diagnostic algorithm (training set) and the rest for testing. While recording and analyzing the test dataset, the researchers were only aware the patients suffered some dizziness, and were kept blind to the exact diagnoses till the end of study. EVestG field potentials (FPs) and their firing pattern, in response to several whole body tilt stimuli from both left and right ears were extracted. We investigated several features of the extracted FPs in response to each of side, back/forward, rotation, up/down, supine rotation, and supine up/down tilt stimulations, and selected the top five features showing the most significant differences between ...Continue Reading

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Citations

Mar 27, 2019·The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry·Brian J LithgowPaul B Fitzgerald
Nov 29, 2017·Scientific Reports·Abdelbaset SuleimanZahra Moussavi
Jun 18, 2017·Frontiers in Systems Neuroscience·Daniel J BrownIan S Curthoys

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