Applications of microfluidics in microalgae biotechnology: A review

Biotechnology Journal
Yi-Je Juang, Jo-Shu Chang

Abstract

Microalgae have been one of the important sources for biofuel production owing to their competitive advantages such as no need to tap into the global food supply chain, higher energy density, and absorbing carbon dioxide to mitigate global warming. One of the key factors to ensure successful biofuel production is that it requires not only bioprospecting of the microalgae with high lipid content, high growth rate and tolerance to environmental parameters but also on-site monitoring of the cultivation process and optimization of the culturing conditions. However, as the conventional techniques usually involve in complicated procedures, or are time-consuming or labor intensive, microfluidics technology offers an attractive alternative to resolve these issues. In this review, applications of microfluidics to bioprospecting in microalgae biotechnology were discussed such as cell identification, cell sorting/screening, cell culturing and cell disruption. In addition, utilization of microalgae in micro-sized fuel cells and microfluidic platforms for biosensing was addressed. This review reports the recent studies and offers a look into how microfluidics is exploited to tackle the issues encountered in the microalgae biotechnology.

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Citations

Mar 2, 2016·Biotechnology Journal·Jo-Shu Chang, Clemens Posten
Jan 23, 2019·Biotechnology and Applied Biochemistry·Amirhossein GhaemiOmid Asayeshnaeini
May 6, 2019·World Journal of Microbiology & Biotechnology·El-Sayed SalamaByong-Hun Jeon
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Mar 1, 2019·Biotechnology for Biofuels·Pierre BodénèsChun-Yen Wang
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Jun 4, 2021·Journal of Microbiological Methods·Philipp DopplerOliver Spadiut
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Nov 30, 2018·Analytical Chemistry·Daihyun KimAlexandra Ros

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