Applications of p-hydroxyphenacyl (pHP) and coumarin-4-ylmethyl photoremovable protecting groups.

Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society for Photobiology
Richard S GivensJakob Wirz

Abstract

Most applications of photoremovable protecting groups have used o-nitrobenzyl compounds and their (often commercially available) derivatives that, however, have several disadvantages. The focus of this review is on applications of the more recently developed title compounds, which are especially well suited for time-resolved biochemical and physiological investigations, because they release the caged substrates in high yield within a few nanoseconds or less. Together, these two chromophores cover the action spectrum for photorelease from >700 nm to 250 nm.

References

Feb 1, 2000·Trends in Biotechnology·G Dormán, G D Prestwich
Mar 18, 2000·The Journal of Biological Chemistry·X DuS H Kim
Jun 7, 2000·Organic Letters·P G ConradK Kandler
Jul 11, 2002·Journal of the American Chemical Society·Keyong ZouHagan Bayley
Aug 31, 2002·Angewandte Chemie·K ZouH Bayley
Mar 5, 2003·Chembiochem : a European Journal of Chemical Biology·Daniel GeisslerVolker Hagen
Mar 28, 2003·Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society for Photobiology·Anna Paola Pelliccioli, Jakob Wirz
Jun 7, 2003·Organic Letters·Min LuTimothy M Dore
Dec 5, 2003·Organic Letters·Akinobu Z SuzukiToshiaki Furuta
Apr 9, 2004·Journal of the American Chemical Society·Yuri V Il'ichevJakob Wirz
Jun 10, 2004·Bioorganic & Medicinal Chemistry·Kiyo TakaokaKeiko Shimamoto
Aug 10, 2004·Chembiochem : a European Journal of Chemical Biology·Toshiaki FurutaRoger Y Tsien
Feb 8, 2005·Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society for Photobiology·George PapageorgiouJohn E T Corrie
May 11, 2005·Biochemistry·Vishakha R ShembekarGeorge P Hess
Jun 30, 2006·Bioorganic & Medicinal Chemistry Letters·Mariusz SkwarczynskiYoshiaki Kiso
Jul 11, 2006·Angewandte Chemie·Günter Mayer, Alexander Heckel
Dec 13, 2006·Chembiochem : a European Journal of Chemical Biology·Daniel GilbertVolker Hagen
Mar 23, 2007·Organic & Biomolecular Chemistry·Douglas D Young, Alexander Deiters
Mar 28, 2007·Chembiochem : a European Journal of Chemical Biology·Carsten KöttingKlaus Gerwert
Apr 12, 2007·Biochemistry·Vishakha R ShembekarGeorge P Hess
Jun 15, 2007·The Journal of Physical Chemistry. a·Reinhard SchmidtJürgen Bendig
Oct 13, 2007·Organic Letters·Toshiaki FurutaChie Matsuba
May 16, 2008·Chembiochem : a European Journal of Chemical Biology·Takashi KawakamiTeruyuki Nagamune
Jul 1, 2008·Nucleic Acids Research·André Vidal PinheiroJoão Carlos Lima
Sep 27, 2008·Langmuir : the ACS Journal of Surfaces and Colloids·Petra StegmaierAránzazu Del Campo
Oct 18, 2008·Langmuir : the ACS Journal of Surfaces and Colloids·Yukiko KikuchiMizuo Maeda
Nov 6, 2008·Chemical Communications : Chem Comm·Kentaro KatayamaTeruyuki Nagamune
Nov 26, 2008·Chembiochem : a European Journal of Chemical Biology·Atsuhiko TaniguchiYoshiaki Kiso

❮ Previous
Next ❯

Citations

Apr 13, 2013·Journal of the American Chemical Society·Jeremy P OlsonGraham C R Ellis-Davies
Oct 15, 2013·Journal of the American Chemical Society·Jeremy P OlsonGraham C R Ellis-Davies
Jun 13, 2012·The Journal of Organic Chemistry·Viju Balachandran KammathRichard S Givens
Jul 26, 2012·The Journal of Organic Chemistry·Peter SebejJakob Wirz
Oct 13, 2012·The Journal of Organic Chemistry·Richard S GivensKenneth F Stensrud
Feb 15, 2012·The Journal of Physical Chemistry. a·Ĺubica KlíčováJakob Wirz
Jul 7, 2012·Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society for Photobiology·Bokolombe Pitchou NgoyPetr Klán
Feb 13, 2013·Beilstein Journal of Organic Chemistry·Graham Cr Ellis-Davies
Apr 10, 2014·Biochimica Et Biophysica Acta·Doris HöglingerCarsten Schultz
Nov 17, 2015·Accounts of Chemical Research·Tomáš ŠolomekPetr Klán
Mar 11, 2016·The Journal of Physical Chemistry. B·Amanda L HoukChristopher G Elles
Sep 18, 2015·Organic Letters·Tomáš SlaninaPetr Klán
Sep 17, 2015·The Journal of Organic Chemistry·Iwona BownikPetr Klán
May 27, 2017·Physical Chemistry Chemical Physics : PCCP·L-M HerzigJ Wachtveitl
Feb 16, 2017·Physical Chemistry Chemical Physics : PCCP·L J G W van WilderenJ Bredenbeck
Feb 19, 2013·Angewandte Chemie·Guillaume BortPeter I Dalko
Oct 10, 2018·Angewandte Chemie·Shuang SunGonçalo J L Bernardes
Mar 9, 2019·Advanced Materials·Lei LiPavel A Levkin
Nov 13, 2013·Chemistry : a European Journal·Ludovic FournierLudovic Jullien
Dec 7, 2013·Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society for Photobiology·Sanjeewa N SenadheeraRichard S Givens
Jun 20, 2017·Current Protocols in Nucleic Acid Chemistry·Geeta MeherRadhakrishnan P Iyer
Apr 5, 2017·Journal of Fluorescence·S SamundeeswariJ Tonannavar
Feb 7, 2015·Advanced Materials·Chunyan BaoHe Tian
Aug 28, 2020·Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society for Photobiology·Thomas FieldRichard S Givens
Oct 18, 2013·Organic & Biomolecular Chemistry·Xinjing TangLihe Zhang
May 7, 2019·Chemical Science·Maxime KlausenMireille Blanchard-Desce
Jul 28, 2019·Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society for Photobiology·Nareshbabu KamathamV Ramamurthy
Oct 20, 2017·Chemistry : a European Journal·Edoardo TortiVladimir Sindelar
Dec 14, 2018·Organic & Biomolecular Chemistry·Eliška ProcházkováOndřej Baszczyňski
Mar 13, 2020·Chemical Communications : Chem Comm·Thilanga N PahattugeSteven A Soper
Jan 8, 2020·Photochemistry and Photobiology·Junko UsukuraNobuaki Koga
Sep 24, 2014·Beilstein Journal of Organic Chemistry·Sanjeewa N SenadheeraRichard S Givens
Jan 17, 2020·ChemPlusChem·Maxime KlausenMireille Blanchard-Desce
Jun 16, 2015·ChemMedChem·Melanie ZindlerChristian Peifer
Apr 10, 2018·Chemical Science·Giovanni BassolinoPablo Rivera-Fuentes
Jul 8, 2020·International Journal of Molecular Sciences·Sofia MunicoyMartin F Desimone
Feb 6, 2020·The Journal of Organic Chemistry·Shengzhuang TangSeok Ki Choi

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.