PMID: 15362524Sep 15, 2004Paper

Applied study on small-dose growth hormone supplement for aging-related symptom complex

Zhonghua nan ke xue = National journal of andrology
Xiansheng ZhangYiran Huang

Abstract

To assess the response of aging-related symptom complex to small-dose supplement of growth hormone. Thirty patients, aged 42 to 77, with aging-related symptom complex and normal serum testosterone were studied. Each subject received growth hormone at the dosage of 0.04 U/kg, 3 times/week for six months. Before and after treatment, body weight, grip strength, abdomen circumference, IPSS, uroflow rate, prostate volume, serum testosterone, cholesterol, triglyceride, PSA, IGF-1, glucose and side effects were determined in every case. Self Rating Scale used by Bosphorus university was adopted. After the treatment, the rating scores were significantly improved, grip strength and serum level of IGF-1 increased, and abdomen circumference and serum cholesterol decreased. Whereas, IPSS, uroflow rate, prostate volume, serum testosterone, triglyceride, PSA, glucose and body weight were not significantly changed. Six months treatment with small-dose growth hormone can improve aging-related symptom complex with little adverse effect.

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