Applying amide proton transfer-weighted MRI to distinguish pseudoprogression from true progression in malignant gliomas

Journal of Magnetic Resonance Imaging : JMRI
Bo MaJinyuan Zhou

Abstract

To assess amide proton transfer-weighted (APTW) imaging features in patients with malignant gliomas after chemoradiation and the diagnostic performance of APT imaging for distinguishing true progression from pseudoprogression. After approval by the Institutional Review Board, 32 patients with clinically suspected tumor progression in the first 3 months after chemoradiation were enrolled and scanned at 3T. Longitudinal routine magnetic resonance imaging (MRI) changes and medical records were assessed to confirm true progression versus pseudoprogression. True progression was defined as lesions progressing on serial imaging over 6 months, and pseudoprogression was defined as lesions stabilizing or regressing without intervention. The APTWmean and APTWmax signals were obtained from three to five regions of interests for each patient and compared between the true progression and pseudoprogression groups. The diagnostic performance was assessed with receiver operating characteristic curve analysis. The true progression was associated with APTW hyperintensity (APTWmean  = 2.75% ± 0.42%), while pseudoprogression was associated with APTW isointensity to mild hyperintensity (APTWmean  = 1.56% ± 0.42%). The APTW signal intensities were si...Continue Reading

References

Oct 28, 2003·Journal of Magnetic Resonance Imaging : JMRI·Susan K HobbsMark D Bednarski
Dec 4, 2003·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Jinyuan ZhouPeter C M van Zijl
Mar 11, 2005·The New England Journal of Medicine·Roger StuppUNKNOWN National Cancer Institute of Canada Clinical Trials Group
May 3, 2008·The Lancet Oncology·Dieta BrandsmaMartin J van den Bent
Sep 26, 2008·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Jinyuan ZhouPeter C M van Zijl
Apr 8, 2009·Current Neurology and Neuroscience Reports·Jennifer L Clarke, Susan Chang
Mar 17, 2010·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Patrick Y WenSusan M Chang
Jul 16, 2010·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·He ZhuJinyuan Zhou
Apr 10, 2012·International Journal of Radiation Oncology, Biology, Physics·Silun WangJinyuan Zhou
Apr 17, 2012·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Zhongliang ZuDaniel F Gochberg
May 12, 2012·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Tao JinSeong-Gi Kim
Aug 22, 2012·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Adrienne N DulaSeth A Smith
Feb 27, 2013·Journal of Magnetic Resonance Imaging : JMRI·Jinyuan ZhouJaishri O Blakeley
May 15, 2013·Journal of Neuro-oncology·Graeme F WoodworthPeter C Burger
Oct 25, 2013·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Stefanie J C G HectorsKlaas Nicolay
Mar 13, 2014·Proceedings of the National Academy of Sciences of the United States of America·Koji SagiyamaMasaya Takahashi
Jan 7, 2015·Journal of Neuro-oncology·Akihiko SakataKaori Togashi
Mar 25, 2015·Integrative Biology : Quantitative Biosciences From Nano to Macro·Mingxi YaoJie Yan
Apr 14, 2015·Proteome Science·Peng ZhangLiwei Zhang
Aug 14, 2015·Journal of Magnetic Resonance Imaging : JMRI·Yi ZhangJinyuan Zhou

❮ Previous
Next ❯

Citations

Jul 2, 2016·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Yi ZhangJinyuan Zhou
Mar 1, 2017·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Desmond H Y TseN Jon Shah
Jun 2, 2017·Magnetic Resonance in Medical Sciences : MRMS : an Official Journal of Japan Society of Magnetic Resonance in Medicine·Yuki KanazawaMitsue Miyazaki
May 8, 2018·Journal of Magnetic Resonance Imaging : JMRI·Stefanie C ThustMarion Smits
Jun 13, 2018·Radiology·Benjamin King Hong LawJing Yuan
Aug 21, 2018·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Hye-Young HeoJinyuan Zhou
May 15, 2018·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Ouri CohenChristian T Farrar
Nov 6, 2018·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Yin WuHairong Zheng
Mar 13, 2019·Journal of Magnetic Resonance Imaging : JMRI·Yong-Lan HeZheng-Yu Jin
Jun 19, 2019·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Hye-Young HeoJinyuan Zhou
Jun 23, 2019·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Rachel W ChanAngus Z Lau
Aug 10, 2017·Journal of Magnetic Resonance Imaging : JMRI·Kyle M JonesMark D Pagel
Aug 21, 2019·Journal of Magnetic Resonance Imaging : JMRI·Jie LiuZhongping Chen
Mar 20, 2020·Journal of Magnetic Resonance Imaging : JMRI·Fabrício Guimarães GonçalvesSuyash Mohan
Sep 25, 2020·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Ruibin LiuYi Zhang
Dec 5, 2018·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Sahrish QamarJing Yuan
Apr 10, 2020·Topics in Magnetic Resonance Imaging : TMRI·Seyed Ali NabavizadehRonald L Wolf
Jul 3, 2019·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Yi ZhangPaul A Bottomley
Sep 2, 2017·Expert Review of Neurotherapeutics·Norbert GalldiksKarl-Josef Langen
Jul 11, 2018·Molecular Imaging and Biology : MIB : the Official Publication of the Academy of Molecular Imaging·Lu YuMin Chen
Jan 12, 2020·Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging·Alipi V BonmJerome J Graber
Mar 7, 2020·Frontiers in Oncology·Lorena ConsolinoDario Livio Longo
Feb 6, 2020·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Yi ZhangDan Wu
Mar 30, 2018·Journal of Neuro-oncology·Hatef MehrabianGreg J Stanisz
Jun 11, 2019·Frontiers in Neuroscience·Thomas SartorettiSabine Sartoretti-Schefer
Jan 22, 2019·Journal of Magnetic Resonance Imaging : JMRI·Jinyuan ZhouShanshan Jiang
Oct 28, 2018·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Shanshan JiangJinyuan Zhou
Nov 17, 2020·Frontiers in Psychiatry·Joseph J ShafferJohn A Wemmie

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cancer Imaging

Imaging techniques, including CT and MR, have become essential to tumor detection, diagnosis, and monitoring. Here is the latest research on cancer imaging.