Applying the miniaturization technologies for biosensor design

Biosensors & Bioelectronics
Burak Derkus

Abstract

Microengineering technologies give us some opportunities in developing high-tech sensing systems that operate with low volumes of samples, integrates one or more laboratory functions on a single substrate, and enables automation. These millimetric sized devices can be produced for only a few dollars, which makes them promising candidates for mass-production. Besides electron beam lithography, stencil lithography, nano-imprint lithography or dip pen lithography, basic photolithography is the technique which is extensively used for the design of microengineered sensing systems. This technique has some advantages such as easy-to-manufacture, do not require expensive instrumentation, and allow creation of lower micron-sized patterns. In this review, it has been focused on three different type of microengineered sensing devices which are developed using micro/nano-patterning techniques, microfluidic technology, and microelectromechanics system based technology.

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Citations

Nov 9, 2018·Journal of Immunoassay & Immunochemistry·Liliana-Roxana BalahuraHassan Y Aboul-Enein
Oct 1, 2020·Journal of Functional Biomaterials·John H T LuongBansi D Malhotra
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Aug 7, 2020·Biosensors·Yi-Chen Ethan Li, I-Chi Lee
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Mar 22, 2020·Biomaterials·Jefferson FrigugliettiFatima A Merchant
Dec 16, 2021·Chemical Reviews·Charalampos PitsalidisRóisín M Owens

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