Applying the pragmatic-explanatory continuum indicator summary to the implementation of a physical activity coaching trial in chronic obstructive pulmonary disease

Nursing Outlook
Huong Q NguyenKaren J Coleman

Abstract

Observational studies show that physical inactivity is associated with worse outcomes in chronic obstructive pulmonary disease (COPD). Despite practice guidelines recommending regular physical activity (PA), there are no large-scale experimental studies to confirm that patients at high risk for COPD exacerbations can increase their PA and consequently, have improved outcomes. The purpose of this case study is to describe the use of a widely accepted pragmatic trials framework for the design and implementation of a pragmatic clinical trial (PCT) of PA coaching for COPD in a real-world setting. The aim of the trial was to determine the effectiveness of a 12-month PA coaching intervention (Walk On!) compared to standard care for 2,707 patients at high risk for COPD exacerbations from a large integrated health care system. The descriptions of our implementation experiences are anchored within the pragmatic-explanatory continuum indicator summary (PRECIS-2) framework. Facilitators of PCT implementation include early and ongoing engagement and support of multiple stakeholders including patients, health system leaders, administrators, physician champions, and frontline clinicians, an organizational/setting that prioritizes positive li...Continue Reading

Associated Clinical Trials

Jun 23, 2015·Huong Q2 NguyenHuong Q2 Nguyen

Citations

Feb 21, 2019·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·Janet SchlossKieran Cooley
Jan 11, 2022·The Cochrane Database of Systematic Reviews·Jade SchrijverTanja W Effing

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