Appropriate end points for the characterization of behavioral changes in developmental toxicology

Environmental Health Perspectives
V CuomoE Alleva

Abstract

The present paper is devoted to second- and higher-tier test methods for the characterization of behavioral changes produced in rodents by exposure to noxious agents during development. The paper analyzes a series of end points that are informative about specific processes and underlying regulatory mechanisms but require greater technical sophistication and larger investments than first-tier end points. This applies to ultrasonic emissions in successive postnatal periods; to mother-pup interactions, including appropriate cross-fostering controls; to social (including sexual) interaction tests from the infantile to the young adult stage; and to a variety of conditioning and learning tests using both positive and negative reinforcement.

References

Mar 1, 1979·Developmental Psychobiology·J Myslivecek, J Hassmannová
Aug 1, 1977·Animal Behaviour·R J BlanchardM J Kelley
Jan 1, 1978·British Journal of Pharmacology·S E File, J R Hyde
Apr 27, 1978·Archives of Toxicology·H R MüschH Greim
Mar 1, 1978·Developmental Psychobiology·R H Bauer
Apr 1, 1978·Journal of Comparative and Physiological Psychology·D Ray, Z M Nagy
Jan 1, 1977·Experimental Aging Research·M C McNamaraA T Miller
Jul 1, 1976·Zeitschrift für Tierpsychologie·A K Dixon, J H Mackintosh
Oct 1, 1975·Journal of Comparative and Physiological Psychology·H Anisman
Sep 28, 1992·Behavioural Brain Research·I Brouette-LahlouM Vigouroux
May 1, 1992·Neurotoxicology and Teratology·M S GolubM E Gershwin
Nov 1, 1991·Kidney International·P D Walker, S V Shah
Nov 1, 1991·Trends in Pharmacological Sciences·J T Winslow, T R Insel
Jan 1, 1991·Neuroscience and Biobehavioral Reviews·G LaviolaE Alleva
Jan 1, 1990·Neuroscience and Biobehavioral Reviews·D C Blanchard, R J Blanchard
Feb 20, 1990·European Journal of Pharmacology·R CagianoV Cuomo
Jan 1, 1990·Annual Review of Psychology·N E SpearJ A Jagielo
May 1, 1986·Pharmacology, Biochemistry, and Behavior·T R InselR B Mayor
Jul 1, 1989·Journal of Animal Science·J G Vandenbergh
Jan 1, 1985·Neuroscience and Biobehavioral Reviews·S E File
Apr 1, 1986·Pharmacology, Biochemistry, and Behavior·A Fernández-GuastiC Beyer
Nov 1, 1986·Behavioral and Neural Biology·E Alleva, G Calamandrei
Jan 1, 1988·Psychopharmacology·R G Lister, L A Hilakivi
Mar 1, 1987·Neurotoxicology and Teratology·V CuomoR Cagiano
Jan 1, 1988·Physiology & Behavior·R J BlanchardD C Blanchard
Nov 1, 1986·Behavioral and Neural Biology·R N Levin, R E Johnston
Oct 1, 1986·Physiology & Behavior·H Takeuchi, S Kawashima
Jan 1, 1985·Behavioral and Neural Biology·F Schenk
Dec 1, 1985·Psychological Reports·K J Flannelly, L Flannelly
Apr 1, 1974·Physiology & Behavior·J R Alberts
Jan 1, 1972·Developmental Psychobiology·G J Egger, P J Livesey
Feb 1, 1973·Physiology & Behavior·R B Jones, N W Nowell
Jun 29, 1973·Psychopharmacologia·D A PowellJ R Holley
Nov 1, 1973·Behavioral Biology·F H Bronson, H M Marsden

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Citations

Apr 1, 1996·Environmental Health Perspectives·B KuligD Peakall
Jul 1, 2009·Environmental Toxicology and Pharmacology·Kristin I FolvenAnne-Katrine Lundebye
Apr 7, 2016·Neuroscience and Biobehavioral Reviews·Judith R HombergAllan V Kalueff
Dec 5, 2012·The Journal of Toxicological Sciences·Saeed IvaniSeyed Reza Fatemi Tabatabaei
Feb 8, 2011·Neurobiology of Learning and Memory·Xiao-Rui ChengYong-Xiang Zhang
Jul 30, 2003·Genes, Brain, and Behavior·I Branchi, L Ricceri
May 26, 2009·Toxicological Sciences : an Official Journal of the Society of Toxicology·Chris N GloverAnne-Katrine Lundebye
Feb 14, 1998·Toxicology and Industrial Health·E AllevaD Santucci

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