Aptamer-Modified Nanoparticles in Medical Applications

Advances in Biochemical Engineering/biotechnology
Alina EilersJohanna G Walter

Abstract

Since aptamers have been selected against a broad range of target structures of medical interest and nanoparticles are available with diverse properties, aptamer-modified nanoparticles can be used in various diagnostic and therapeutic applications. While the aptamer is responsible for specificity and affinity of the conjugate, the nanoparticles' function varies from signal generation in diagnostic approaches to drug loading in drug delivery systems. Within this chapter different medical applications of aptamer-modified nanoparticles will be summarized and underlying principles will be described.

Citations

Nov 5, 2020·ACS Applied Materials & Interfaces·Meihua LinFan Xia

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