PMID: 6111309Jan 1, 1981Paper

APUD system (problems of structural and functional organization, histogenesis and pathology)

Arkhiv patologii
I M Kvetnoiĭ

Abstract

The aspects of structure and function of the APUD-system under normal and pathological conditions are analysed. New terms and concepts (apudocyte, apudoblast, apudogenesis, apudopathies) applicable to the APUD-system are introduced. It is suggested that some apudocytes originate from polypotential stem cells. The dysfunctions of the APUD-system (apudopathies) are described, their classification is suggested, and the role of apudocytes in the endogenous mechanisms of oncogenesis is analysed.

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