Aquaporins: water channel proteins of the cell membrane

Progress in Histochemistry and Cytochemistry
Kuniaki TakataYuki Tajika

Abstract

Aquaporins (AQP) are integral membrane proteins that serve as channels in the transfer of water, and in some cases, small solutes across the membrane. They are conserved in bacteria, plants, and animals. Structural analyses of the molecules have revealed the presence of a pore in the center of each aquaporin molecule. In mammalian cells, more than 10 isoforms (AQP0-AQP10) have been identified so far. They are differentially expressed in many types of cells and tissues in the body. AQP0 is abundant in the lens. AQP1 is found in the blood vessels, kidney proximal tubules, eye, and ear. AQP2 is expressed in the kidney collecting ducts, where it shuttles between the intracellular storage sites and the plasma membrane under the control of antidiuretic hormone (ADH). Mutations of AQP2 result in diabetes insipidus. AQP3 is present in the kidney collecting ducts, epidermis, urinary, respiratory, and digestive tracts. AQP3 in organs other than the kidney may be involved in the supply of water to them. AQP4 is present in the brain astrocytes, eye, ear, skeletal muscle, stomach parietal cells, and kidney collecting ducts. AQP5 is in the secretory cells such as salivary, lacrimal, and sweat glands. AQP5 is also expressed in the ear and eye...Continue Reading

Citations

Aug 19, 2006·Current Genetics·Nina PetterssonStefan Hohmann
Sep 5, 2007·Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology·Miwa SuzukiKiyoshi Asahina
Jul 3, 2008·Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology·Ewan M CampbellAlan S Bowman
Aug 26, 2009·Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology·Miwa Suzuki
Jul 29, 2005·Histochemistry and Cell Biology·Yuki TajikaKuniaki Takata
Apr 22, 2005·Histochemistry and Cell Biology·Toshiyuki MatsuzakiKuniaki Takata
Jan 9, 2007·Histochemistry and Cell Biology·Takahiro HasegawaKuniaki Takata
Jun 21, 2008·Histochemistry and Cell Biology·Kuniaki TakataTakahiro Hasegawa
Nov 29, 2005·Pflügers Archiv : European journal of physiology·Robert B WellnerBruce J Baum
Feb 18, 2011·Pflügers Archiv : European journal of physiology·Bayram EdemirThomas Weide
May 1, 2007·Cell and Tissue Research·Yuki TajikaHiroshi Yorifuji
Jan 12, 2008·Cell and Tissue Research·Miwako Matsuki-FukushimaHiroshi Sugiya
Jun 15, 2007·Functional & Integrative Genomics·Kerrie L Forrest, Mrinal Bhave
Dec 1, 2007·Journal of Biological Physics·Mario ParisiRoxana Toriano
Jan 28, 2012·Journal of Huazhong University of Science and Technology. Medical Sciences = Hua Zhong Ke Ji Da Xue Xue Bao. Yi Xue Ying De Wen Ban = Huazhong Keji Daxue Xuebao. Yixue Yingdewen Ban·Wenmin JinLijun Yao
Apr 16, 2009·Visual Neuroscience·Melinda J GoodyearBarbara M Junghans
Jul 13, 2006·European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP)·Jose RussoIrma H Russo
Oct 19, 2007·Clinical and Experimental Pharmacology & Physiology·Hai-Tao LiangTong-Hui Ma
Mar 17, 2006·Acta Pharmacologica Sinica·Fang WangTong-Hui Ma
Aug 19, 2005·Molecular and Cellular Biology·Yoshiyuki MorishitaKenichi Ishibashi
Sep 20, 2011·American Journal of Physiology. Heart and Circulatory Physiology·Wei-Qing HanPin-Lan Li
Jun 16, 2012·Journal of Dental Research·L ZhengP Papagerakis
Jan 29, 2008·Acta Histochemica Et Cytochemica·Takeshi SuzukiKuniaki Takata
Mar 19, 2009·Acta Histochemica Et Cytochemica·Yuko IidaKuniaki Takata
Feb 4, 2010·Acta Histochemica Et Cytochemica·Toshiyuki MatsuzakiKuniaki Takata
Jan 28, 2012·Acta Histochemica Et Cytochemica·Toshiyuki MatsuzakiHitoshi Ozawa
Jun 12, 2012·Acta Histochemica Et Cytochemica·Takeo AokiToshiyuki Matsuzaki
Dec 5, 2012·Acta Histochemica Et Cytochemica·Toshiyuki MatsuzakiKuniaki Takata
Mar 13, 2014·Acta Histochemica Et Cytochemica·Taketo SusaToshiyuki Matsuzaki
May 21, 2010·The Journal of Veterinary Medical Science·Sachi KuwaharaMakoto Seki
Feb 23, 2011·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·Ouahiba Mesbah-BenmessaoudValérie Grange-Messent
Oct 17, 2007·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·Seishi MaedaMakoto Seki
Jun 17, 2009·PLoS Biology·Gerhard FischerKarin Lindkvist-Petersson
Apr 13, 2006·Archives of Histology and Cytology·Abduxukur AblimitKuniaki Takata

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