Aqueous-phase aminolysis: approach for the analysis of epoxides in water

Analytical Chemistry
Stuart J KhanE Cydnie Bedford

Abstract

Trace concentrations of small soluble epoxides are suspected byproducts of drinking water ozonation. However, adequate characterization of epoxide formation is currently limited by the lack of suitable analytical methods to target these chemicals in dilute, but complex aqueous solutions. One potential approach is presented here based on aqueous-phase aminolysis. The method also employs solid-phase extraction, silylation of the solvent extract, and analysis by gas chromatography-mass spectrometry. This approach is demonstrated to be effective for the selective analysis of the epoxides 1,2-epoxybutane, epichlorohydrin, and epifluorohydrin in water with optimized method detection limits of 5-10 ng/L.

References

Dec 22, 1999·Analytical Chemistry·H Weinberg
Jun 30, 2004·Water Research·Alex A YavichSusan J Masten
Nov 30, 2004·Veterinary Parasitology·Walter Q Betancourt, Joan B Rose

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Citations

Sep 9, 2009·Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences·Howard S Weinberg
May 15, 2009·Rapid Communications in Mass Spectrometry : RCM·Cristina RipollésFélix Hernández
May 24, 2008·Analytical Chemistry·Susan D Richardson

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