Aqueous shunts for glaucoma.

The Cochrane Database of Systematic Reviews
Don S MincklerBrian A Francis

Abstract

Aqueous shunts are employed for intraocular pressure (IOP) control in primary and secondary glaucomas that fail medical, laser, and other surgical therapies. This review compares aqueous shunts for IOP control and safety. We searched CENTRAL, MEDLINE, PubMed, EMBASE, NRR all in January 2006, LILACS to February 2004 and reference lists of included trials. We included all randomized and quasi-randomized trials in which one arm of the study involved shunts. Two authors independently extracted data for included studies and a third adjudicated discrepancies. We contacted investigators for missing information. We used fixed-effect models and summarized continuous outcomes using mean differences. We included fifteen trials with a total of 1153 participants with mixed diagnoses. Five studies reported details sufficient to verify the method of randomization but only two had adequate allocation concealment. Data collection and follow-up times were variable.Meta-analysis of two trials comparing Ahmed implant with trabeculectomy found trabeculectomy resulted in lower mean IOPs 11 to 13 months later (mean difference 3.81 mm Hg, 95% CI 1.94 to 5.69 mm Hg). Meta-analysis of two trials comparing double-plate Molteno implant with the Schocket s...Continue Reading

Citations

Nov 10, 2009·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Lars ChoritzHagen Thieme
Jun 3, 2014·Indian Journal of Ophthalmology·Nikhil Shreeram ChoudhariLingam Vijaya
Mar 12, 2017·Advances in Therapy·Ivano RivaLuciano Quaranta
Jul 28, 2017·The Cochrane Database of Systematic Reviews·Victoria L TsengJoseph Caprioli
Dec 2, 2015·The Cochrane Database of Systematic Reviews·Xue WangAnne Coleman
Jul 15, 2015·The Cochrane Database of Systematic Reviews·Mingjuan Lisa ZhangHenry Jampel
Mar 16, 2012·The Cochrane Database of Systematic Reviews·Alex PollockUma Shahani
Oct 4, 2013·The Cochrane Database of Systematic Reviews·Arathi SimhaKristina Lindsley
Mar 11, 2019·The Cochrane Database of Systematic Reviews·Monica F ChenAnne L Coleman
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Feb 7, 2020·The Cochrane Database of Systematic Reviews·Arathi SimhaKristina B Lindsley
Sep 14, 2012·The Cochrane Database of Systematic Reviews·Jennifer BurrAnja Tuulonen
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Feb 9, 2017·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Brian A FrancisAlex Huang
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