ARA and EADV criteria for classification of systemic lupus erythematosus in patients with cutaneous lupus erythematosus

Dermatology : International Journal for Clinical and Investigative Dermatology
A Parodi, A Rebora

Abstract

To verify (1) how many patients with cutaneous lupus erythematosus (CLE) fulfill 4 or more American Rheumatism Association (ARA) and European Academy of Dermatology and Venereology (EADV) criteria for classification of systemic lupus erythematosus (SLE); (2) which criteria are mostly fulfilled; (3) the severity of the disease in patients fulfilling criteria; (4) how many patients with systemic involvement fail to fulfill 4 ARA and EADV criteria. We studied 207 patients with chronic and subacute CLE, classified according to ARA and EADV criteria. Twenty-four patients with localized discoid (L-DLE; 21.8%), 22 with disseminated discoid (D-DLE; 30.5%) and 7 with subacute CLE (SCLE; 28%) had 4 or more ARA criteria. With EADV criteria, these figures fell to 7 (6.4%), 7 (9.7%) and 6 (24%), respectively. Only 3 L-DLE (2.7%), 5 D-DLE (6.9%) and 3 SCLE cases (12%) defined as SLE by ARA criteria and 1, 3 and 3, respectively, by EADV criteria had a renal or neurological disorder, hemolytic anemia and/or thrombocytopenia, vasculitis or serositis. ARA criteria did not classify 7 patients with a similar visceral involvement, while EADV criteria failed in 11 patients. In our patients, ARA criteria showed a sensitivity of 88%, a specificity of ...Continue Reading

Citations

Mar 21, 2006·Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete·A KuhnG Bonsmann
Jul 2, 2005·Autoimmunity Reviews·Victoria P Werth
Mar 29, 2000·The British Journal of Dermatology·A ParodiA Rebora
May 10, 2002·The British Journal of Dermatology·J WenzelI Boehm
Jul 15, 2004·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Hayet KaaroudHédi Ben Maiz
Nov 26, 2013·Actas dermo-sifiliográficas·J A Avilés IzquierdoP Lázaro Ochaita
Mar 6, 2010·Rheumatic Diseases Clinics of North America·Rachel S KleinVictoria P Werth
Dec 20, 2005·The Journal of Dermatology·Idil UnalGulsen Kandiloglu
Nov 30, 2007·Pediatrics International : Official Journal of the Japan Pediatric Society·Shori TakahashiKensuke Harada
Jan 16, 2014·Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG·Mirjana ZiemerManfred Kunz
Jan 11, 2005·La Revue de médecine interne·S BéjiH Ben Maiz
Jul 6, 2004·Clinics in Dermatology·Beate Tebbe
Nov 12, 2021·Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG·Anne WeldemannMirjana Ziemer
Nov 24, 2021·Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG·Anne WeldemannMirjana Ziemer

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