PMID: 9537269Apr 16, 1998Paper

Arabian Peninsula men tend to insulin resistance and cardiovascular risk seen in South Asians

Tropical Medicine & International Health : TM & IH
R N PughM A White

Abstract

To test the hypothesis that peninsular Arabs and South Asians share a tendency to insulin resistance, differing from other ethnic groups living in the United Arab Emirates (UAE). A representative sample of 358 apparently healthy men aged 35-49 years drawn from a multiethnic office-based workforce in the UAE was tested. The sample included a reference group of expatriate South Asians, in whom insulin resistance has already been described as the cause of high coronary heart disease (CHD) mortality. All subjects were screened for CHD risk factors, including glucose tolerance and 2-h serum insulin determinations. There was a high prevalence of previously undiagnosed cases of diabetes (10.1%) and hypertension (14.2%). South Asian and peninsular Arab men shared the tendency to significantly higher 2-h glucose and insulin levels, lower HDL cholesterol concentrations and abdominal obesity especially compared to Europeans, who were five times less likely to be glucose-intolerant (OR 5.40, P = 0.015). Three other Arab groups were intermediate in most trends. Susceptibility to insulin resistance in Arabian peninsula men is strongly supported, suggesting that control of obesity and promotion of exercise are the best approach to CHD prevent...Continue Reading

References

Nov 1, 1988·British Heart Journal·P M McKeigueR A Riemersma
Jan 1, 1986·Diabetes/metabolism Reviews·V A KoivistoR A DeFronzo
Feb 1, 1994·Diabetologia·D I PhillipsC Osmond
Dec 1, 1995·Diabetic Medicine : a Journal of the British Diabetic Association·M G AsfourH King
Dec 1, 1995·Diabetic Medicine : a Journal of the British Diabetic Association·W H HermanF DeStefano

❮ Previous
Next ❯

Citations

Jul 18, 2002·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Conrad B Blum
Jul 1, 2010·Asia-Pacific Journal of Public Health·Tarik M Ramahi
Mar 11, 2003·European Journal of Clinical Nutrition·C J MillerI B Hashim

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiovascular Disease Pathophysiology

Cardiovascular disease involves several different processes that contribute to the pathological mechanism, including hyperglycemia, inflammation, atherosclerosis, hypertension and more. Vasculature stability plays a critical role in the development of the disease. Discover the latest research on cardiovascular disease pathophysiology here.

CV Disorders & Type 2 Diabetes

This feed focuses on the association of cardiovascular diseases in patients with type 2 diabetes.

Related Papers

International Journal of Obesity : Journal of the International Association for the Study of Obesity
S FrankB Schultes
BMJ : British Medical Journal
M J Davies, I P Gray
Obesity Surgery
Ryan HolzwarthBasir Tareen
© 2022 Meta ULC. All rights reserved