PMID: 7523895Oct 16, 1994Paper

Arabidopsis assay for mutagenicity

Mutation Research
T GichnerJ Velemínský

Abstract

Four laboratories, two in the Czech Republic (Brno and Prague) and two in the CIS (Moscow and Duschanbe), participated in the International Programme on Chemical Safety's (IPCS) collaborative study to evaluate the utility of the most commonly used plant test systems, including the Arabidopsis thaliana assay, for assessing the mutagenic potential of environmental agents. Out of the five compounds evaluated in the Arabidopsis assay, three compounds, i.e., ethyl methanesulfonate, N-methyl-N-nitrosourea, and azidoglycerol, were reported to be mutagenic by all four participating laboratories. Sodium azide (NaN3) demonstrated a negative response in all four laboratories, whereas maleic hydrazide was reported to be weakly mutagenic by one laboratory and nonmutagenic by the other three laboratories.

Citations

Jun 4, 2013·Trends in Plant Science·Joakim PalovaaraDolf Weijers
Jan 13, 1998·Current Opinion in Cell Biology·G JürgensT Steinmann
Nov 24, 1999·Trends in Plant Science·J MarienfeldA Brennicke
Feb 13, 2001·Current Opinion in Plant Biology·M Meijer, J A Murray
Mar 6, 1999·Current Opinion in Plant Biology·B Scheres, T Berleth
Dec 18, 2010·Mutagenesis·M MisíkS Knasmueller
Apr 28, 2006·PLoS Biology·Mitchell P LevesquePhilip N Benfey
May 17, 2008·PLoS Genetics·Olivier FrançoisNoah A Rosenberg
Nov 12, 2013·Mutation Research. Genetic Toxicology and Environmental Mutagenesis·Petr GrúzMasatomi Shimizu
Mar 17, 1997·Mutation Research·E González-César, P Ramos-Morales
Dec 2, 2004·Mutation Research·Paul A White, Larry D Claxton

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