Arabidopsis BTB/POZ protein-dependent PENETRATION3 trafficking and disease susceptibility

Nature Plants
Hailiang MaoMarkus Grebe

Abstract

The outermost cell layer of plant roots (epidermis) constantly encounters environmental challenges. The epidermal outer plasma membrane domain harbours the PENETRATION3 (PEN3)/ABCG36/PDR8 ATP-binding cassette transporter that confers non-host resistance to several pathogens. Here, we show that the Arabidopsis ENDOPLASMIC RETICULUM-ARRESTED PEN3 (EAP3) BTB/POZ-domain protein specifically mediates PEN3 exit from the endoplasmic reticulum and confers resistance to a root-penetrating fungus, providing prime evidence for BTB/POZ-domain protein-dependent membrane trafficking underlying disease resistance.

References

Jan 22, 2005·The Plant Journal : for Cell and Molecular Biology·Monika DieterlePascal Genschik
Oct 10, 2008·Molecular Plant-microbe Interactions : MPMI·Marco LoehrerUlrich Schaffrath
Mar 3, 2010·Proceedings of the National Academy of Sciences of the United States of America·Junpei TakanoToru Fujiwara
May 11, 2010·Current Biology : CB·Lukasz LangowskiJirí Friml
Feb 24, 2012·Nature·Lingyan JinMichael Rape
Jan 4, 2013·Molecular Biology of the Cell·Matyás FendrychViktor Zársky
Jul 3, 2013·Molecular Plant-microbe Interactions : MPMI·Xiu-Fang XinSheng Yang He
Jul 10, 2013·Proceedings of the National Academy of Sciences of the United States of America·William Underwood, Shauna C Somerville
Apr 22, 2017·The Journal of Cell Biology·Amita GorurRandy Schekman

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Methods Mentioned

BETA
PCR
immunoprecipitation
fluorescence recovery after photobleaching

Software Mentioned

Fiji
eFP Browser

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