PMID: 11607555Jul 3, 1995Paper

Arabidopsis signal transduction mutant defective in chemically and biologically induced disease resistance

Proceedings of the National Academy of Sciences of the United States of America
T DelaneyJ Ryals

Abstract

Plants possess multiple resistance mechanisms that guard against pathogen attack. Among these are inducible systems such as systemic acquired resistance (SAR). SAR is activated by pathogen exposure and leads to an increase in salicylic acid (SA), high-level expression of SAR-related genes, and resistance to a spectrum of pathogens. To identify components of the signal transduction pathways regulating SAR, a mutant screen was developed that uses 2,6-dichloroisonicotinic acid as an activator of SAR gene expression and pathogen resistance, followed by assays for resistance to the fungal pathogen Peronospora parasitica. Mutants from this screen were subsequently examined to assess their defense responses. We describe here a recessive mutation that causes a phenotype of insensitivity to chemical and biological inducers of SAR genes and resistance. These data indicate the existence of a common signaling pathway that couples these diverse stimuli to induction of SAR genes and resistance. Because of its non-inducible immunity phenotype, we call this mutant nim1. Although nim1 plants fail to respond to SA, they retain the ability to accumulate wild-type levels of SA, a probable endogenous signal for SAR. Further, the ability of nim1 pla...Continue Reading

References

Jun 1, 1992·The Plant Cell·S UknesJ Ryals
May 1, 1990·The Plant Cell·E Koch, A Slusarenko
Nov 1, 1993·Molecular Plant-microbe Interactions : MPMI·S PotterJ Ryals
May 20, 1994·Cell·R A DietrichJ L Dangl
Aug 1, 1993·Proceedings of the National Academy of Sciences of the United States of America·D AlexanderE Ward
Nov 18, 1994·Science·T P DelaneyJ Ryals

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Citations

Nov 22, 2007·Molecular Genetics and Genomics : MGG·Chang-Jie JiangHiroshi Takatsuji
Sep 15, 2005·Plant Molecular Biology·Jeffrey D Pylatuik, Pierre R Fobert
Oct 7, 2010·Plant Molecular Biology·Shoji SuganoHiroshi Takatsuji
May 11, 2013·Journal of Biosciences·Riddhi DattaSharmila Chattopadhyay
Mar 6, 1999·Current Opinion in Plant Biology·R W Innes
Mar 6, 1999·Current Opinion in Plant Biology·X Dong
Jan 13, 2001·Current Opinion in Immunology·B P ThommaB P Cammue
Feb 1, 1996·Current Opinion in Immunology·K ShirasuC Lamb
May 7, 2002·Trends in Plant Science·Uwe ConrathBrigitte Mauch-Mani
Jun 15, 1999·Trends in Plant Science·K Maleck, R A Dietrich
Jun 22, 2001·Current Opinion in Plant Biology·X Dong
Jul 23, 2003·Current Opinion in Plant Biology·Jyoti Shah
Feb 15, 2002·The Plant Journal : for Cell and Molecular Biology·Daniel H AvivJeffery L Dangl
Jul 29, 1998·The Plant Journal : for Cell and Molecular Biology·Z H HeB D Kohorn
Nov 9, 2000·The Plant Journal : for Cell and Molecular Biology·J DewdneyF M Ausubel
Aug 8, 2001·The Plant Journal : for Cell and Molecular Biology·M S ChernP C Ronald
Jun 13, 2002·The Plant Journal : for Cell and Molecular Biology·Jurriaan TonCorné M J Pieterse
Jun 13, 2002·The Plant Journal : for Cell and Molecular Biology·Marta Berrocal-LoboRoberto Solano
Jul 9, 2002·The Plant Journal : for Cell and Molecular Biology·Thierry GenoudJean-Pierre Métraux
Sep 7, 2012·Molecular Plant-microbe Interactions : MPMI·Taha Abd El RahmanKamal Bouarab
Nov 25, 2011·Molecular Plant-microbe Interactions : MPMI·Ragiba MakandarJyoti Shah
Apr 15, 2005·Molecular Plant-microbe Interactions : MPMI·Ashis NandiJyoti Shah

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