Archaeal histones: structures, stability and DNA binding

Biochemical Society Transactions
John N ReeveD J Soares


Structures, stability and DNA-binding properties have been established for archaeal histones from mesophiles, thermophiles and hyperthermophiles. Most archaeal histones are simply histone folds that are stabilized by dimer formation. Archaeal histones and the histone folds of the eukaryotic nucleosome core histones share a common ancestry and bind and wrap DNA similarly using conserved residues. The histone-fold residues that stabilize dimer-dimer interactions within an archaeal histone core contribute to determining archaeal histone-DNA affinity.


Dec 8, 2007·Extremophiles : Life Under Extreme Conditions·Christine D Hardy, Patrick K Martin
May 27, 2009·Origins of Life and Evolution of the Biosphere : the Journal of the International Society for the Study of the Origin of Life·Robert W Griffith
Nov 17, 2012·Nucleic Acids Research·Rosalie P C DriessenRemus T Dame
Oct 5, 2010·Archaea : an International Microbiological Journal·Jörg Soppa
Sep 27, 2014·International Journal of Molecular Sciences·Valeria VisoneMaria Ciaramella
May 31, 2012·Science China. Life Sciences·ZhenFeng ZhangLi Huang
Mar 23, 2010·Journal of Theoretical Biology·Sonja J ProhaskaDavid C Krakauer
Feb 24, 2006·Journal of Molecular Biology·Victoria L MarshStephen D Bell
Nov 19, 2015·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·Dave Speijer
Jun 7, 2005·Trends in Microbiology·Stephen D Bell
Sep 2, 2015·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·James McInerneyMary J O'Connell
Dec 19, 2013·Archaea : an International Microbiological Journal·Anja SpangThijs J G Ettema
Jan 27, 2011·Biochemical Society Transactions·Anna ValentiMaria Ciaramella
Jan 27, 2011·Biochemical Society Transactions·Rosalie P C Driessen, Remus T Dame
Feb 17, 2009·Structure·J ZlatanovaKen van Holde
Oct 24, 2007·International Journal for Parasitology·Lakshminarayan M IyerL Aravind
Jun 5, 2016·Cellular and Molecular Life Sciences : CMLS·Zhe Lyu, William B Whitman
Jan 1, 2011·Life·Erik D Andrulis
Dec 29, 2018·Molecular Microbiology·Travis J SandersThomas J Santangelo
Apr 13, 2005·The Journal of Biological Chemistry·Victoria L MarshStephen D Bell
May 7, 2015·Nature Reviews. Microbiology·Eveline PeetersRemus T Dame
Aug 21, 2007·Expert Review of Proteomics·Michael S Cosgrove
Feb 14, 2018·Proceedings. Biological Sciences·Elvira Hörandl, Dave Speijer
Nov 7, 2019·ELife·Maria RojecTobias Warnecke
Oct 26, 2005·The Journal of Biological Chemistry·José María Eirín-LópezJuan Ausió

Related Concepts

Histone antigen
Hot Temperature
Homologous Sequences, Amino Acid
Nucleosome Core Particle
DNA Binding
Circular Dichroism, Vibrational
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