Archaeosomes: an excellent carrier for drug and cell delivery

Drug Delivery
Gurmeet KaurAmit K Goyal

Abstract

Archaeosomes as liposomes made with one or more ether lipids that are unique to the domain of Archaeobacteria, found in Archaea constitute a novel family of liposome. Achaean-type lipids consist of archaeol (diether) and/or caldarchaeol (tetraether) core structures. Archaeosomes can be produced using standard procedures (hydrated film submitted to sonication, extrusion and detergent dialysis) at any temperature in the physiological range or lower, therefore making it possible to encapsulate thermally stable compounds. Various physiological as well as environmental factors affect its stability. Archaeosomes are widely used as drug delivery systems for cancer vaccines, Chagas disease, proteins and peptides, gene delivery, antigen delivery and delivery of natural antioxidant compounds. In this review article, our major aim was to explore the applications of this new carrier system in pharmaceutical field.

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Citations

Mar 25, 2016·Therapeutic Delivery·Vibhuti AgrahariAshim K Mitra
Feb 22, 2017·Organic & Biomolecular Chemistry·Geoffray LericheJerry Yang
Aug 31, 2020·International Journal of Mycobacteriology·Nur Ellene Mat LuwiArmando Acosta
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Nov 12, 2020·Advanced Therapeutics·Joydeb Majumder, Tamara Minko
Apr 9, 2021·Progress in Lipid Research·Alexsandra Conceição ApolinárioLuciana Biagini Lopes

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