Architecture of intraluminal thrombus removed from abdominal aortic aneurysm.

Journal of Thrombosis and Thrombolysis
Paweł MatusikAnetta Undas

Abstract

Little is known about architecture of intraluminal thrombus (ILT) in abdominal aortic aneurysm (AAA). We present a 74-year-old woman with AAA and high cardiovascular risk. Scanning electron microscopy of ILT removed during surgery showed that its luminal layer is relatively rich in fibrin fibers forming irregular compact structure with low amounts of erythrocytes and platelets, while abluminal portion is composed of densely packed fibrin with caniculi. The structure of ILT may differ largely among AAA patients contrary to previous findings and may reveal large dense fibrin-rich areas deprived of cells, which impair fibrinolysis and stabilize the thrombus size.

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Citations

Nov 17, 2010·Proceedings of the National Academy of Sciences of the United States of America·Antonio Di GennaroJesper Z Haeggström
Apr 13, 2011·Journal of Vascular and Interventional Radiology : JVIR·Fausto LabrutoJesper Swedenborg
Dec 15, 2015·Materials Science & Engineering. C, Materials for Biological Applications·Balakrishnan SivaramanAnand Ramamurthi
Jul 14, 2018·Arteriosclerosis, Thrombosis, and Vascular Biology·Carsten Behr AndersenHans Christian Beck
Sep 17, 2011·Arteriosclerosis, Thrombosis, and Vascular Biology·D Julian A ScottRobert A S Ariëns
May 20, 2015·Annals of Biomedical Engineering·Jianhua Tong, Gerhard A Holzapfel
Sep 27, 2020·Biomaterials·Nisakorn YodsanitShaoqin Gong

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