ARDS and influenza A (H1N1): patients' characteristics and management in intensive care unit. A literature review

Annales Françaises D'anesthèsie Et De Rèanimation
S JaberG Chanques

Abstract

Novel influenza A (H1N1) at the origin of the 2009 pandemic flu developed mainly in subjects of less than 65 years contrary to the seasonal influenza, which usually developed in elderly patients of more than 65 years. Elderly subjects are partly protected by old meetings with close stocks. Influenza A(H1N1) can arise in serious forms within 60 to 80% of cases a fulminant acute respiratory distress syndrome (ARDS) "malignant and fulminant influenza" in subjects without any comorbidity, which makes the gravity and the fear of this influenza. The fact that this influenza A (H1N1) can develop in healthy young patients and evolve in few hours to a severe ARDS with a refractory hypoxemia gave to the foreground the possible interest of the recourse to extracorporeal oxygenation (ECMO) in some selected severe ARDS (5-10%). The first publications of patients admitted in intensive care unit (ICU) for severe influenza A (H1N1) often associated to an ARDS reported a mortality rate from 15 to 40%. This mortality variability may be explained in part by different studied populations, ARDS characteristics and human and material resources in the ICUs between the countries. Indeed, the highest mortality rates (30-40%) have been reported by in Me...Continue Reading

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Citations

Oct 29, 2013·Annales Françaises D'anesthèsie Et De Rèanimation·A SelvesT Geeraerts
Jul 21, 2014·Annales Françaises D'anesthèsie Et De Rèanimation·Y Coisel, S Jaber
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Apr 3, 2012·Journal of Korean Medical Science·Soonhak KwonHyeeun Seo
Jun 21, 2019·The Journal of Experimental Medicine·Hye Kyung LimShen-Ying Zhang
Jan 1, 2012·Public Health Reviews·Steven S Coughlin
Jun 10, 2011·Influenza and Other Respiratory Viruses·Hassen DamakMounir Bouaziz
Jun 26, 2021·Frontiers in Molecular Biosciences·Jing GaoYuejie Yang

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