PMID: 9419086Jan 7, 1998Paper

Are acoustic neuromas encapsulated tumors?

Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery
T C KuoLawrence H Pitts

Abstract

In articles and chapters on the subject of acoustic neuroma, it is almost invariably stated that they are well-encapsulated tumors. During surgical procedures, blunt mechanical dissection defines a natural subsurface cleavage plane that leaves intact a several millimeter thick rind of tumor surface. Occasionally, as a concession to neural integrity, less than complete resection is elected, leaving behind this "capsular" remnant. To clarify the nature of the surface of acoustic neuromas and to test whether this long held description is indeed correct, a microscopic analysis of 10 surgical specimens was performed. A wedge was harvested from the free surface of the tumor in the mid cerebellopontine angle that included a large, undisturbed section of the tumor surface. Histologic analysis showed that for most of the tumor surface only an extremely thin (3 to 5 microm) layer of connective tissue envelops the tumor. Neoplastic Schwann cells, which extend essentially to the margin of the tumor, were found to be somewhat flattened and compressed in the vicinity of the surface. Although acoustic neuromas are surrounded by a continuous layer of connective tissue, it is so exceptionally thin (on average less than the diameter of a red blo...Continue Reading

References

Jan 1, 1992·British Journal of Neurosurgery·R H LyeJ M Dutton
May 1, 1991·Neurosurgery·J B BedersonM G Yasargil
Nov 1, 1991·Neurosurgery·B S ThedingerC M Luetje
Sep 1, 1990·Acta Oto-laryngologica·J PerreJ F Foncin
Jan 1, 1989·Archives of Oto-rhino-laryngology·G FortonJ Marquet
Mar 1, 1993·Journal of Neuropathology and Experimental Neurology·R A Sobel

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Citations

Mar 11, 2004·American Journal of Otolaryngology·William M MendenhallPatrick J Antonelli
May 13, 1999·Surgical Neurology·W E SnyderR R Smith
Mar 4, 2000·Surgical Neurology·Y KumonN Yanagihara
Jan 17, 2004·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Dov C BlochLawrence H Pitts
Dec 21, 2000·International Journal of Radiation Oncology, Biology, Physics·H ShiratoK Miyasaka
Dec 21, 2000·International Journal of Radiation Oncology, Biology, Physics·M FussM Wannenmacher
Dec 3, 2002·International Journal of Radiation Oncology, Biology, Physics·Marianna KarpinosShiao Y Woo
Feb 3, 2000·International Journal of Radiation Oncology, Biology, Physics·O W MeijerB J Slotman
Feb 9, 2005·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Wha-Joon Lee, Jon E Isaacson
Aug 1, 2008·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Emmanuel LescanneAnita Pollak
Mar 26, 2009·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Gonzalo N Esquia-MedinaOlivier Sterkers
Nov 27, 2002·Journal of Neurosurgery·M Gazi Yaşargil
Nov 1, 2006·The Laryngoscope·Sri Kiran ChennupatiNatasha Mirza
Jan 19, 2012·The Laryngoscope·Matthew L CarlsonMichael J Link
Sep 1, 2004·International Journal of Radiation Oncology, Biology, Physics·John C FlickingerL Dade Lunsford
Feb 9, 2006·International Journal of Radiation Oncology, Biology, Physics·Stephanie E CombsDaniela Schulz-Ertner
Aug 23, 2005·International Journal of Radiation Oncology, Biology, Physics·Stephanie E CombsJürgen Debus
Jan 12, 2011·Neurosurgery·Michihiro KohnoMunehiro Yokoyama
Dec 4, 2014·Arquivos de neuro-psiquiatria·Eduardo A S VellutiniOswaldo Laercio M Cruz
Apr 19, 2000·Arquivos de neuro-psiquiatria·F LeitãoF Leitão Filho

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