Abstract
It is debated whether chronic urogenital inflammations and infections may trigger the formation of antisperm antibodies (ASA) in semen. To evaluate the formation of ASA in defined chronic inflammatory and infectious diseases of the male reproductive tract (MRT). Three hundred sixty-five patients retrospectively enrolled in a single center were categorized as having National Institutes of Health (NIH) category II chronic prostatitis (n=38), NIH category IIIa chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) (n=59), NIH category IIIb CP/CPPS (n=213), chronic epididymitis (n=34), and chronic urethritis (n=21). Forty-five age-matched men served as controls. All subjects underwent microbiologic and cytologic analysis for common bacteria, yeasts, and mycoplasma using the four-glass test. Urine samples, ejaculates, and urethral swabs were analyzed with polymerase chain reaction (PCR) for Chlamydia trachomatis and Neisseria gonorrhea. Semen analysis followed World Health Organization (WHO) standards. ASA in seminal plasma were analyzed using the mixed agglutination reaction (MAR) test. The overall positive detection rate of clinically significant levels (> or = 50% of spermatozoa coated by ASA) of IgG and IgA antibodies was 1....Continue Reading
References
Jan 1, 1990·Urology·S MićićR Dotlić
Aug 1, 1990·Urology·J P JarowD G Assimos
Mar 1, 1994·American Journal of Reproductive Immunology : AJRI·A HeidenreichU H Engelmann
Mar 20, 1998·American Journal of Reproductive Immunology : AJRI·D A GubinW H Kutteh
Nov 7, 1998·Fertility and Sterility·S Mazumdar, A S Levine
Jan 14, 1999·Human Reproduction·J A KrapezA H Balen
Jul 28, 1999·JAMA : the Journal of the American Medical Association·J N KriegerJ C Nickel
Dec 3, 1999·Human Reproduction Update·W WeidnerM Ludwig
Oct 9, 2001·International Journal of STD & AIDS·P J Horner, UNKNOWN European Branch of the International Union against Sexually Transmitted Infection and the European Office of the World Healt
Feb 13, 2002·Journal of Reproductive Immunology·Masahiko MaegawaToshihiro Aono
Oct 24, 2003·European Urology·Daniel S EngelerHubert John
Nov 5, 2003·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Esko VeräjänkorvaPasi Pöllänen
Jan 14, 2004·International Journal of Andrology·K KomoriH Fujioka
Nov 20, 2004·American Journal of Reproductive Immunology : AJRI·Dimitrina DimitrovaLyudmil Nakov
Jul 12, 2005·European Urology·G R DohleUNKNOWN EAU Working Group on Male Infertility
Nov 30, 2005·European Urology·Jakob LacknerMichael Marberger
Aug 15, 2006·European Urology·Giuseppe PennaLuciano Adorini
Nov 17, 2006·European Urology·Sandra MazzoliRiccardo Bartoletti
Apr 17, 2007·BJU International·Nicolai LeonhartsbergerHannes Steiner
Mar 14, 2008·Andrologia·W WeidnerT Diemer
Aug 30, 2008·Andrologia·M MarconiW Weidner
Citations
May 8, 2010·Der Urologe. Ausg. A·H-C SchuppeW Weidner
Jul 13, 2011·World Journal of Urology·A RuszW Weidner
Jul 17, 2013·World Journal of Urology·W WeidnerF Wagenlehner
Sep 11, 2014·Human Reproduction·Monika FijakAndreas Meinhardt
Nov 30, 2013·The Urologic Clinics of North America·Bassel G Bachir, Keith Jarvi
Mar 6, 2012·Gynécologie, obstétrique & fertilité·F BoitrelleM Albert
Dec 10, 2009·European Urology·Marcelo Marconi, Wolfgang Weidner
Aug 22, 2008·European Urology·Tolga Akman, Ateş Kadioglu
Feb 11, 2012·International Journal of Andrology·P Hoover, R K Naz
May 28, 2014·American Journal of Reproductive Immunology : AJRI·Mónica H Vazquez-LevinCarolina Veaute
Oct 10, 2012·Fertility and Sterility·Andrea GarollaCarlo Foresta
Oct 16, 2016·Journal of Reproductive Immunology·Yumei JiangXiaojing Bai
Jun 2, 2009·European Urology·Sandra MazzoliRiccardo Bartoletti
Apr 13, 2018·Human Reproduction Update·Monika FijakAndreas Meinhardt
Sep 19, 2019·Vaccines·Vickram A SWanpen Chaicumpa
May 10, 2017·Investigative and Clinical Urology·Fukashi YamamichiMasato Fujisawa
May 11, 2017·Journal of Endocrinological Investigation·R A CondorelliS La Vignera
Jun 10, 2017·Deutsches Ärzteblatt International·Hans-Christian SchuppeWolfgang Weidner
Sep 22, 2021·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Yuki KatoAtsushi Mizokami