Are atopy and specific IgE to mites and molds important for adult asthma?

The Journal of Allergy and Clinical Immunology
M S JaakkolaJouni J K Jaakkola

Abstract

Atopy is known to be important for childhood asthma, but this is to our knowledge the first study on its relation with development of asthma in adulthood. We addressed the role of atopy, measured as total IgE and Phadiatop, and of specific IgE antibodies to mites and molds in development of adult-onset asthma. A population-based incident case-control study was conducted in the Pirkanmaa District in Southern Finland. All new clinically diagnosed cases of asthma 21-63 years of age were recruited 1997-2000 in the study district. A random sample of the source population formed the controls. A total of 485 cases and 665 controls provided a serum sample. Diagnosis of asthma was based on demonstration of reversibility in lung function investigations. Subjects with previous asthma were excluded. Phadiatop score and IgE antibodies were analyzed with the UniCAP system. The adjusted odds ratio of asthma increased with total IgE and Phadiatop score in a dose-dependent pattern. IgE antibodies to house dust mite and storage mite were significantly related to an increased risk of asthma. Among molds, increased risk of asthma was seen in relation to IgE antibodies to Aspergillus fumigatus and Cladosporium herbarum. Population attributable frac...Continue Reading

References

Mar 1, 1990·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·P M MatricardiR D'Amelio
Sep 1, 1995·American Journal of Respiratory and Critical Care Medicine
Jul 1, 1996·American Journal of Respiratory and Critical Care Medicine·H M BoezenB Rijcken
Dec 10, 1999·American Journal of Epidemiology·M S Jaakkola, J J Jaakkola
Mar 11, 2000·American Journal of Respiratory and Critical Care Medicine·P G Holt
May 11, 2002·Environmental Health Perspectives·Maritta S JaakkolaJouni J K Jaakkola
Nov 5, 2002·The European Respiratory Journal·R BarracloughS C Stenton
Dec 4, 2003·American Journal of Public Health·Maritta S JaakkolaJouni J K Jaakkola

❮ Previous
Next ❯

Citations

Dec 2, 2010·International Archives of Occupational and Environmental Health·Maritta S JaakkolaJouni J K Jaakkola
Apr 2, 2008·Current Allergy and Asthma Reports·Jay M PortnoyKevin Kennedy
Aug 12, 2009·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Kemp W BundyBrian P Leaderer
Aug 21, 2009·Occupational Medicine·Femi AdewoleP S Burge
Sep 25, 2007·Eukaryotic Cell·Tobias M Hohl, Marta Feldmesser
Oct 30, 2010·The European Respiratory Journal·R LietzénM Koskenvuo
Mar 7, 2012·BMC Medical Research Methodology·Maritta S Jaakkola, Jouni J K Jaakkola
Aug 20, 2009·Environmental Health : a Global Access Science Source·Penpatra SripaiboonkijMaritta S Jaakkola
Jul 20, 2007·Environmental Health Perspectives·Maritta S Jaakkola, Jouni J K Jaakkola
Dec 30, 2011·PloS One·Aino RantalaMaritta S Jaakkola
Sep 16, 2009·CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne·Padmaja SubbaraoMalcolm R Sears
Apr 3, 2014·Respiratory Medicine·Samu HernbergMaritta S Jaakkola
Jul 20, 2010·American Journal of Epidemiology·Jouni J K JaakkolaMaritta S Jaakkola
Oct 28, 2008·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·Amina Hamed Ahmad Al ObaidiJasim Mohamad Al Janabi
Sep 4, 2009·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·Francis Fu-Sheng WuJulian Crane
Oct 23, 2009·Journal of Immunotoxicology·Cherie M Pucheu-HastonMarsha D W Ward
Jan 31, 2012·The Journal of Allergy and Clinical Immunology·Alan P KnutsenAndrew J Wardlaw
Sep 25, 2007·The Journal of Allergy and Clinical Immunology·Samuel J ArbesDarryl C Zeldin
May 3, 2007·The Journal of Allergy and Clinical Immunology·David B Peden, Robert K Bush
Sep 22, 2012·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·J MengUNKNOWN Children's Mercy Center for Environmental Health
Jul 7, 2011·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·M W GerbaseN Probst-Hensch
Oct 12, 2013·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·Sachin N BaxiWanda Phipatanakul
Oct 5, 2015·Allergology International : Official Journal of the Japanese Society of Allergology·Yuma Fukutomi, Masami Taniguchi
Aug 25, 2011·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·O M IgeC O Olopade
Feb 10, 2012·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·Francis Fu-Sheng WuRobert Siebers
May 4, 2015·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·A B OzturkH Keskin
Jun 29, 2013·The Journal of Allergy and Clinical Immunology·Marijke AmelinkElisabeth H Bel
Aug 28, 2014·The Journal of Allergy and Clinical Immunology·Richard A SharpeNicholas J Osborne
Sep 19, 2007·The Korean Journal of Parasitology·Joon-Soo ParkSung-Ho Kim
Jul 6, 2014·Clinical Reviews in Allergy & Immunology·Christian E Sandrock, Andrew Norris
Aug 6, 2015·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·A PatelisA Malinovschi
Aug 9, 2016·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Akihiko TanakaHironori Sagara
Feb 21, 2008·American Journal of Rhinology·Liisa K AiraksinenElina M Toskala
Apr 17, 2014·Clinical and Translational Allergy·David W DenningSvetlana Sergejeva
Jan 25, 2019·American Journal of Industrial Medicine·Pål GraffUlf Flodin
Jan 24, 2019·Current Opinion in Allergy and Clinical Immunology·Juan M Inclan-RicoMark C Siracusa
Jun 11, 2019·BMJ Open Respiratory Research·Jouni J K JaakkolaMaritta S Jaakkola
Oct 25, 2016·Allergy·S R Del GiaccoL Bjermer
Nov 28, 2012·International Archives of Allergy and Immunology·Anne-Elie CarsinJordi Sunyer
Jun 9, 2017·Wiener klinische Wochenschrift·Slavomír PerečinskýL'ubomír Legáth

❮ Previous
Next ❯

Related Concepts

Related Feeds

Aspergillosis

Aspergillosis is the name given to a wide variety of diseases caused by infection by fungi of the genus Aspergillus. Aspergillosis occurs in chronic or acute forms which are clinically very distinct. Most cases of acute aspergillosis occur in patients with severely compromised immune systems. Chronic colonization or infection can cause complications in people with underlying respiratory illnesses. Discover the latest research on aspergillosis here.

Asthma

This feed focuses in Asthma in which your airways narrow and swell. This can make breathing difficult and trigger coughing, wheezing and shortness of breath.

Atopic Dermatitis

Atopic dermatitis is a chronic inflammatory genetically determined disease of the skin marked by increased ability to form reagin (IgE), with increased susceptibility to allergic rhinitis and asthma, and hereditary disposition to a lowered threshold for pruritus. Discover the latest research on atopic dermatitis here.

Allergy and Asthma

Allergy and asthma are inflammatory disorders that are triggered by the activation of an allergen-specific regulatory t cell. These t cells become activated when allergens are recognized by allergen-presenting cells. Here is the latest research on allergy and asthma.

Aspergillosis (ASM)

Aspergillosis is the name given to a wide variety of diseases caused by infection by fungi of the genus Aspergillus. Aspergillosis occurs in chronic or acute forms which are clinically very distinct. Most cases of acute aspergillosis occur in patients with severely compromised immune systems. Chronic colonization or infection can cause complications in people with underlying respiratory illnesses. Discover the latest research on aspergillosis here.

Allergies & Environmental Factors

Environmental factors are strongly associated with the prevalence of allergies and are an increasing health concern worldwide. Discover the latest research on Allergies and Environmental Factors here.

© 2021 Meta ULC. All rights reserved