Are BMP-15 and GDF-9 primary determinants of ovulation quota in mammals?

Trends in Endocrinology and Metabolism : TEM
R Kelly MooreShunichi Shimasaki

Abstract

How do mammals control the number of eggs that are ovulated during the estrous and menstrual cycles? Our understanding of this fundamental process has grown in recent years as a result of intense efforts to identify and characterize the genes that control the ovulation quota. An increasing body of evidence shows that two oocyte-specific factors, bone morphogenetic protein-15 (BMP-15) and growth and differentiation factor-9 (GDF-9), play crucial roles in determining folliculogenesis, ovulation rate and litter size in sheep and mice. In this article, we review recent advances on the physiological, cellular and molecular roles of BMP-15 and GDF-9, which, potentially, link these oocyte-secreted factors to the species-specific determination of ovulation quota and litter size in mammals.

References

Jan 1, 1995·Molecular Endocrinology·S A McGrathS J Lee
Sep 22, 2000·The Journal of Biological Chemistry·F OtsukaS Shimasaki
Apr 26, 2001·Proceedings of the National Academy of Sciences of the United States of America·P MulsantJ M Elsen
May 25, 2001·Reproduction : the Official Journal of the Society for the Study of Fertility·G W MontgomeryK P McNatty
Jun 21, 2001·Proceedings of the National Academy of Sciences of the United States of America·S E YiK M Lyons
Feb 28, 2002·Proceedings of the National Academy of Sciences of the United States of America·John J EppigFrank L Pendola
Mar 9, 2002·Reviews in Endocrine & Metabolic Disorders·Xuemei Wu, Martin M Matzuk
Mar 9, 2002·Reviews in Endocrine & Metabolic Disorders·Chang Suk SuhGregory F Erickson
Jun 5, 2002·Molecular and Cellular Endocrinology·S M GallowayG H Davis
Jun 6, 2002·Proceedings of the National Academy of Sciences of the United States of America·Fumio Otsuka, Shunichi Shimasaki
Nov 7, 2002·The Journal of Biological Chemistry·R Kelly MooreShunichi Shimasaki
May 6, 2003·Science·Karin HübnerHans R Schöler
Feb 11, 2004·Endocrine Reviews·Shunichi ShimasakiGregory F Erickson

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Citations

May 15, 2009·Reproduction : the Official Journal of the Society for the Study of Fertility·Jennifer L JuengelKenneth P McNatty
Sep 23, 2009·Reproduction : the Official Journal of the Society for the Study of Fertility·P M LokmanS Adachi
Sep 13, 2012·Reproduction : the Official Journal of the Society for the Study of Fertility·Jia Yi LinKenneth P McNatty
Apr 9, 2011·Reproduction : the Official Journal of the Society for the Study of Fertility·Karen L ReaderJennifer L Juengel
Apr 6, 2005·Proceedings of the National Academy of Sciences of the United States of America·Osamu HashimotoShunichi Shimasaki
Nov 6, 2007·Proceedings of the National Academy of Sciences of the United States of America·Anilkumar BettegowdaGeorge W Smith
Jul 5, 2006·Proceedings of the National Academy of Sciences of the United States of America·Osamu YoshinoShunichi Shimasaki
Jun 19, 2008·Reproductive Biology and Endocrinology : RB&E·Marissa A BowdenGuiying Nie
Apr 10, 2010·Human Reproduction·Jodie N PainterGrant W Montgomery
Oct 23, 2009·Molecular Human Reproduction·David G Mottershead, Andrew J Watson
Aug 29, 2013·Molecular Human Reproduction·G W MontgomeryD R Nyholt
Feb 11, 2015·Reproduction : the Official Journal of the Society for the Study of Fertility·S Al-SamerriaG Almahbobi
Mar 2, 2006·Human Genetics·Hridesh DixitLalji Singh
Oct 31, 2009·Endocrine Journal·Fumio Otsuka
Feb 10, 2017·Twin Research and Human Genetics : the Official Journal of the International Society for Twin Studies·Ana C MardiniUrsula Matte
Sep 7, 2006·The Journal of Clinical Endocrinology and Metabolism·James S PalmerGrant W Montgomery
Jan 24, 2007·Human Reproduction Update·Darryl L Russell, Rebecca L Robker
Feb 26, 2013·Twin Research and Human Genetics : the Official Journal of the International Society for Twin Studies·Elizabeth M C Van der StroomCornelis B Lambalk
Nov 26, 2013·Molecular Reproduction and Development·Sarah L FieldNicolas M Orsi
Nov 21, 2007·Human Reproduction Update·Chantal HoekstraGrant W Montgomery
Jan 13, 2011·Molecular Reproduction and Development·Fumio OtsukaShunichi Shimasaki
Jan 12, 2012·Endocrinology·Courtney M SimpsonCraig A Harrison
Jun 21, 2020·Molecular Ecology Resources·Belinda R WrightCatherine E Grueber
Jan 8, 2008·Human Reproduction Update·Robert B GilchristJeremy G Thompson
May 30, 2013·Reproduction in Domestic Animals = Zuchthygiene·G M F de CamargoH Tonhati
Jun 2, 2006·Reproduction, Fertility, and Development·Kenneth P McNattyJennifer L Juengel
Jan 5, 2011·Reproduction in Domestic Animals = Zuchthygiene·Fernanda Paulini, Eduardo O Melo
Jul 1, 2021·Journal of Ovarian Research·Eleonora FerrariniMassimo Tonacchera
Apr 13, 2010·Reproductive Biomedicine Online·Hridesh DixitLalji Singh

❮ Previous
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