Are central executive functions working in patients with focal frontal lesions?

Neuropsychologia
Pilar Andrés, Martial Van der Linden

Abstract

The aim of this study was to examine the hypothesis of a link between frontal cortex and two executive functions in working memory: the capacity to perform a dual task and the ability to inhibit irrelevant information. A dual task designed to assess the capacity to perform storage and processing simultaneously and a directed forgetting task designed to assess the capacity to actively inhibit no-longer relevant information were administered to a group of patients with focal frontal lesions and to a group of control participants. The results revealed that despite showing reduced short-term storage, frontal patients performed the dual task and inhibited the no-longer relevant information as well as control participants. These findings suggest that not all-executive processes are exclusively sustained by the frontal cortex [Quart J Exp Psychol 9 (1996) 5; Curr Opin Neurobiol 10 (2000) 195; Neuropsychology (1994) 544; The Cognitive Neuropsychology of Alzheimer-type dementia. Oxford, New York: Oxford University Press, 1996].

References

Nov 1, 1991·Journal of Clinical and Experimental Neuropsychology·S W AndersonD Tranel
Apr 1, 1991·Brain : a Journal of Neurology·T Shallice, P W Burgess
Oct 1, 1985·Journal of Neurology, Neurosurgery, and Psychiatry·A G CanavanP H Schurr
Jun 25, 1982·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·T Shallice
Nov 16, 1995·Nature·M D'EspositoM Grossman
Apr 1, 1996·Neuropsychologia·P W Burgess, T Shallice
Jun 1, 1996·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·P W Burgess, T Shallice
Dec 1, 1995·Journal of Clinical and Experimental Neuropsychology·C V AndersonD D Blatter
Oct 29, 1996·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·T Shallice, P Burgess
Jun 23, 1998·Current Opinion in Neurobiology·A Baddeley
Jul 8, 1998·Proceedings of the National Academy of Sciences of the United States of America·J JonidesP A Reuter-Lorenz
Sep 24, 1998·Journal of the International Neuropsychological Society : JINS·A Baddeley
Mar 12, 1999·Science·E E Smith, J Jonides
Apr 3, 1999·Stroke; a Journal of Cerebral Circulation·K R ThulbornM A Just
Jul 8, 1999·Proceedings of the National Academy of Sciences of the United States of America·H GaravanE A Stein
Sep 1, 1999·Brain : a Journal of Neurology·M MussoM Rijntjes
Oct 26, 1999·Neuropsychologia·M D'Esposito, B R Postle
Nov 24, 1999·Journal of the International Neuropsychological Society : JINS·D E FleckS M Strakowski
Feb 7, 2001·Current Opinion in Neurobiology·P A CarpenterE D Reichle
Jun 20, 2000·Cerebral Cortex·H GaravanE A Stein
Sep 27, 2000·Psychological Research·D T Stuss, M P Alexander
Nov 15, 2000·The Journals of Gerontology. Series B, Psychological Sciences and Social Sciences·P Andrés, M Van der Linden
Apr 20, 2001·Journal of Clinical and Experimental Neuropsychology·P Andrés

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Citations

Nov 25, 2005·Experimental Brain Research·Lauren M Potter, Madeleine A Grealy
Sep 1, 2005·European Archives of Psychiatry and Clinical Neuroscience·Ulrich MüllerThomas Becker
Aug 30, 2005·Archives of Clinical Neuropsychology : the Official Journal of the National Academy of Neuropsychologists·Sophie BaudicLatchezar Traykov
Aug 26, 2010·Journal of the International Neuropsychological Society : JINS·Nicholas Morton, Lynne Barker
Aug 5, 2003·BMC Psychiatry·Peter GallagherR Hamish McAllister-Williams
Oct 30, 2013·Cognitive, Affective & Behavioral Neuroscience·Nikki HonzelDiane Swick
May 2, 2008·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Yung-Nien ChenFriederike Schlaghecken
Oct 21, 2006·Neuropsychologia·Pilar AndrésFabrice B R Parmentier
May 4, 2010·Journal of Intellectual Disability Research : JIDR·P WillnerS Dymond
Apr 6, 2006·Neuropsychology·Cindy M de FriasEsther Strauss
Feb 27, 2015·Frontiers in Behavioral Neuroscience·T A DohertyM D Beer
Sep 18, 2014·Frontiers in Behavioral Neuroscience·Annick N TanguayMark B Ferland
Jan 8, 2014·Journal of Clinical and Experimental Neuropsychology·Jérémy BesnardDidier Le Gall
May 29, 2012·Brain : a Journal of Neurology·Martine RousselOlivier Godefroy
Sep 30, 2017·Archives of Clinical Neuropsychology : the Official Journal of the National Academy of Neuropsychologists·Alfredo ArdilaMonica Rosselli

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