Are food compounds able to modulate noxious activities induced by cadmium exposure?

Critical Reviews in Food Science and Nutrition
Carolina Foot Gomes de Moura, Daniel Araki Ribeiro

Abstract

Cadmium is one of the most toxic environmental and industrial pollutants and is able to induce severe injury because it is poorly excreted, accumulating in various organs. This common pollutant is responsible for serious damage in lung, brain, testis, kidney, liver, circulatory system, and bone. Food compounds, such as flavonoids, represent the most abundant polyphenols in human diet and comprise thousands of substances, which are freely available as high-dose dietary supplements. The mechanism of action of these ones consists in free radical scavenging and metal sequestration. The interaction of metal ions with flavonoids leads to chelation and the use of these natural compounds is better than the synthetic ones due to their lower toxic effects. The aim of this review is to describe the role of some food compounds, focusing on flavonoids for modulating noxious biological activities induced by cadmium exposure.

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Citations

Dec 15, 2015·Journal of Trace Elements in Medicine and Biology : Organ of the Society for Minerals and Trace Elements (GMS)·Samuel Rangel ClaudioDaniel Araki Ribeiro
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Jan 8, 2021·Environmental Science and Pollution Research International·Gyanendra SinghDharati Parmar
Mar 20, 2020·Journal of Agricultural and Food Chemistry·Shuo SunPing Zhuang

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