Are gender, comorbidity, and obesity risk factors for postoperative periprosthetic fractures after primary total hip arthroplasty?

The Journal of Arthroplasty
Jasvinder A SinghDavid Lewallen

Abstract

We studied the frequency and patient risk factors for postoperative periprosthetic fractures after primary total hip arthroplasty (THA). With a mean follow-up of 6.3 years, 305 postoperative periprosthetic fractures occurred in 14,065 primary THAs. In multivariable-adjusted Cox regression analyses, female gender (hazard ratio [HR], 1.48; 95% confidence interval [CI], 1.17-1.88), Deyo-Charlson comorbidity score of 2 (HR, 1.74 for score of 2; 95% CI, 1.25-2.43) or 3 or higher (HR, 1.71; 95% CI, 1.26-2.32), and American Society of Anesthesiologist class of 2 (HR, 1.84; 95% CI, 0.90-3.76) or 3 (HR, 2.45; 95% CI, 1.18-5.1) or 4 or higher (HR, 2.68; 95% CI, 0.70-10.28) were significantly associated with higher risk/hazard, and cemented implant, with lower hazard (HR, 0.68; 95% CI, 0.54-0.87) of postoperative periprosthetic fractures. Interventions targeted at optimizing comorbidity management may decrease postoperative fractures after THA.

References

Jun 1, 1992·Journal of Clinical Epidemiology·R A DeyoM A Ciol
Jan 1, 1989·Archives of Orthopaedic and Trauma Surgery·G LöwenhielmJ Kärrholm
Jan 1, 1987·Journal of Chronic Diseases·M E CharlsonR G Douglas
Aug 1, 1974·The Journal of Trauma·R P WhittakerE L Ralston
Oct 1, 1982·Clinical Orthopaedics and Related Research·J S BetheaR B Welch
Mar 1, 1996·Journal of Clinical Epidemiology·W A GhaliM A Moskowitz
Mar 13, 2003·Mayo Clinic Proceedings·Mark W PagnanoRobert T Trousdale
Oct 21, 1961·JAMA : the Journal of the American Medical Association·R D DRIPPSJ E ECKENHOFF
Sep 27, 2003·The Journal of Arthroplasty·Frances WeaverWilliam G Henderson
Mar 17, 2004·Acta Orthopaedica Scandinavica·Roope SarvilinnaK Jorma K Pajamäki
Dec 21, 2005·The Journal of Bone and Joint Surgery. British Volume·H LindahlG Garellick
Mar 15, 2006·Journal of Occupational and Environmental Medicine·D Adam LongGregg Lehman
Apr 6, 2006·JAMA : the Journal of the American Medical Association·Cynthia L OgdenKatherine M Flegal
Jun 8, 2006·The Journal of Bone and Joint Surgery. American Volume·Hans LindahlHenrik Malchau
Apr 4, 2007·The Journal of Bone and Joint Surgery. American Volume·Steven KurtzMichael Halpern
May 1, 2007·Injury·John Franklin, Henrik Malchau
Nov 8, 2007·JAMA : the Journal of the American Medical Association·Dawn E Alley, Virginia W Chang
Dec 7, 2007·The Journal of Bone and Joint Surgery. American Volume·Timothy BhattacharyyaHenrik Malchau
May 3, 2008·The Journal of Bone and Joint Surgery. American Volume·Rad ZderoEmil H Schemitsch
Jan 5, 2011·The Journal of Bone and Joint Surgery. British Volume·R M D MeekC R Howie

❮ Previous
Next ❯

Citations

Jun 29, 2014·Der Radiologe·C A AgtenC W A Pfirrmann
Sep 12, 2014·Expert Review of Medical Devices·Eddie S WuMichael A Mont
Dec 22, 2015·International Orthopaedics·José Carlos MinarroAlberto Damián Delgado-Martínez
Mar 31, 2015·International Orthopaedics·Claudia C Sidler-Maier, James P Waddell
Apr 19, 2015·Arthritis Research & Therapy·Jasvinder A Singh, Rekha Ramachandran
Aug 3, 2014·Injury·Jesús MoretaJosé Luis Martínez-De Los Mozos
May 15, 2012·The Journal of Arthroplasty·James A KeeneyRobert L Barrack
May 16, 2015·The Journal of Arthroplasty·Paul A Toogood, Thomas P Vail
Feb 7, 2015·Gait & Posture·Kyle D HuffmanWilliam M Mihalko
Jul 24, 2014·Scandinavian Journal of Surgery : SJS : Official Organ for the Finnish Surgical Society and the Scandinavian Surgical Society·Y ZhuY Zhang
Nov 28, 2017·European Journal of Orthopaedic Surgery & Traumatology : Orthopédie Traumatologie·Gaetano CarusoLeo Massari
Dec 12, 2018·The Journal of the American Academy of Orthopaedic Surgeons·John A ScanelliJoseph T Moskal
Jan 4, 2020·Clinical Orthopaedics and Related Research·Kristine Ifigenia BunyozAnders Troelsen
Sep 1, 2016·The Journal of the American Academy of Orthopaedic Surgeons·Lee Eric RubinJulio C Defillo-Draiby
Nov 8, 2017·BMC Musculoskeletal Disorders·Andreas VossAugustus D Mazzocca
Feb 23, 2018·Geriatric Orthopaedic Surgery & Rehabilitation·Sheriff D AkinleyeOrry Erez
Feb 6, 2020·The Bone & Joint Journal·Jason S HoellwarthMunjed Al Muderis
Jul 14, 2020·Frontiers in Bioengineering and Biotechnology·Mara TerziniCristina Bignardi
Nov 2, 2019·ANZ Journal of Surgery·Harry ConstantinIan A Harris
May 22, 2021·Journal of Orthopaedics and Traumatology : Official Journal of the Italian Society of Orthopaedics and Traumatology·Matthias LugerAntonio Klasan
Aug 15, 2021·Archives of Orthopaedic and Trauma Surgery·M F R Powell-BownsC E H Scott

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.