Are gestational age, birth weight, and birth length indicators of favorable fetal growth conditions? A structural equation analysis of Filipino infants

Statistics in Medicine
Kenneth A BollenLinda S Adair

Abstract

The fetal origins hypothesis emphasizes the life-long health impacts of prenatal conditions. Birth weight, birth length, and gestational age are indicators of the fetal environment. However, these variables often have missing data and are subject to random and systematic errors caused by delays in measurement, differences in measurement instruments, and human error. With data from the Cebu (Philippines) Longitudinal Health and Nutrition Survey, we use structural equation models, to explore random and systematic errors in these birth outcome measures, to analyze how maternal characteristics relate to birth outcomes, and to take account of missing data. We assess whether birth weight, birth length, and gestational age are influenced by a single latent variable that we call favorable fetal growth conditions (FFGC) and if so, which variable is most closely related to FFGC. We find that a model with FFGC as a latent variable fits as well as a less parsimonious model that has birth weight, birth length, and gestational age as distinct individual variables. We also demonstrate that birth weight is more reliably measured than is gestational age. FFGCs were significantly influenced by taller maternal stature, better nutritional stores i...Continue Reading

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Citations

Jul 22, 2016·PloS One·Rachel A BlakeJennifer F Friedman
Apr 2, 2019·Health Economics·Marie Baguet, Christelle Dumas
Jun 18, 2019·Child Development·Marie Camerota, Michael T Willoughby
Oct 28, 2019·International Journal of Environmental Research and Public Health·Wahida Kihal-TalantikiteSéverine Deguen
Mar 28, 2017·American Journal of Human Biology : the Official Journal of the Human Biology Council·Megan Workman, Karina Kelly

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