Are hemoglobin levels elevated in type 1 diabetes?

Diabetes Care
Baqiyyah N ConwayTrevor J Orchard

Abstract

While lower hemoglobin is generally associated with adverse events in diabetes, we have recently observed in type 1 diabetes that those with overt nephropathy had hemoglobin levels as high as 18.8 g/dl. We thus explored whether hemoglobin concentrations are generally higher in type 1 diabetes. Baseline (1986-1988) hemoglobin levels from the Pittsburgh Epidemiology of Diabetes Complications Study (EDC) of type 1 diabetes were compared with general population data from the National Health and Nutrition Examination Survey (NHANES) III in the same age range as the EDC population (aged 8-48 years). Both male and female EDC study participants had significantly higher hemoglobin levels than their NHANES III counterparts (men: 16.0 vs. 15.1 g/dl, P < 0.0001; women: 14.1 vs. 13.3 g/dl, P < 0.0001). The difference between the two populations was greatest in adolescent female subjects. Hemoglobin levels may be higher in type 1 diabetes than in the general population, which may have important clinical implications.

References

Jul 13, 1999·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·A LevinO Djurdjev
Sep 10, 2004·The Journal of Clinical Endocrinology and Metabolism·Merlin C ThomasGeorge Jerums
May 9, 2006·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·UNKNOWN KDOQI, UNKNOWN National Kidney Foundation
Dec 18, 2007·Annals of Epidemiology·Baqiyyah ConwayTevor Orchard
Nov 11, 2009·Archives of Ophthalmology·Baqiyyah N ConwayTrevor J Orchard

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Citations

Jun 15, 2011·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Se Won OhSuhnggwon Kim
Dec 20, 2012·ISRN Endocrinology·Lisa Stehno-Bittel
May 1, 2012·Survey of Ophthalmology·Sobha SivaprasadJennifer Evans
Apr 28, 2012·Respiratory Physiology & Neurobiology·Juha E PeltonenHeikki O Tikkanen

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