PMID: 7547252Oct 1, 1995Paper

Are Japanese and European gastric cancer the same biological entity? An immunohistochemical study

British Journal of Cancer
J I LivingstoneC Wastell

Abstract

To examine the suggested biological difference between Japanese and British gastric cancers, immunohistochemistry was used to demonstrate eight markers of biological activity in a matched series of 40 Japanese and 33 British cases. There were no differences in the proportions of Japanese and British tumours positive to epidermal growth factor, epidermal growth factor receptor, transforming growth factor alpha, cripto or p53. A significantly greater proportion of British tumours were positive to c-erbB-2 whilst a significantly greater proportion of Japanese tumours were positive to nm23. British tumours had a significantly greater mean proliferating cell nuclear antigen proliferation index than Japanese tumours. These differences could be clinically significant.

Citations

Dec 15, 2000·Oncogene·W LinH C Chen
May 1, 2012·World Journal of Surgical Oncology·Xiaowen LiuYanong Wang
Sep 11, 2014·World Journal of Gastroenterology : WJG·Shaila J MerchantJoseph Kim
Jul 16, 2015·Journal of Surgical Oncology·Vivian E StrongMurray F Brennan
Aug 17, 2004·Annals of Saudi Medicine·Khawla Al KurayaGuido Sauter
Dec 10, 2016·Journal of Cancer Research and Clinical Oncology·Julia KneisslBirgit Luber
Sep 28, 2012·ANZ Journal of Surgery·Xiaowen LiuYanong Wang
Feb 5, 2002·Biochimica Et Biophysica Acta·M G PersicoG Minchiotti

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