Are known cyanotoxins involved in the toxicity of picoplanktonic and filamentous North Atlantic marine cyanobacteria?

Marine Drugs
Bárbara FrazãoV Vasconcelos

Abstract

Eight marine cyanobacteria strains of the genera Cyanobium, Leptolyngbya, Oscillatoria, Phormidium, and Synechococcus were isolated from rocky beaches along the Atlantic Portuguese central coast and tested for ecotoxicity. Strains were identified by morphological characteristics and by the amplification and sequentiation of the 16S rDNA. Bioactivity of dichloromethane, methanol and aqueous extracts was assessed by the Artemia salina bioassay. Peptide toxin production was screened by matrix assisted laser desorption/ionization time of flight mass spectrometry. Molecular analysis of the genes involved in the production of known cyanotoxins such as microcystins, nodularins and cylindrospermopsin was also performed. Strains were toxic to the brine shrimp A. salina nauplii with aqueous extracts being more toxic than the organic ones. Although mass spectrometry analysis did not reveal the production of microcystins or other known toxic peptides, a positive result for the presence of mcyE gene was found in one Leptolyngbya strain and one Oscillatoria strain. The extensive brine shrimp mortality points to the involvement of other unknown toxins, and the presence of a fragment of genes involved in the cyanotoxin production highlight the...Continue Reading

References

Jul 1, 1997·International Journal of Systematic Bacteriology·B A NeilanA E Goodman
Oct 10, 2001·Journal of Bacteriology·K TsugeM Shoda
Nov 17, 2001·Toxicon : Official Journal of the International Society on Toxinology·M PratiG Bernardini
Jan 5, 2002·Applied Microbiology and Biotechnology·E DittmannT Börner
Feb 16, 2002·Environmental Microbiology·M KaebernickB A Neilan
Sep 25, 2002·BMC Biotechnology·José Luis CarballoMaría D García-Grávalos
Jan 4, 2003·Journal of Bacteriology·Guntram ChristiansenElke Dittmann
Mar 14, 2003·Environmental Toxicology·Kim M Fergusson, Christopher P Saint
Oct 11, 2003·Archives of Microbiology·Michael HisberguesThomas Börner
Jan 1, 2004·Proceedings of the National Academy of Sciences of the United States of America·Anne RantalaKaarina Sivonen
Nov 6, 2004·Applied and Environmental Microbiology·Michelle C Moffitt, Brett A Neilan
Mar 2, 2005·Toxicology and Applied Pharmacology·C Wiegand, S Pflugmacher
Mar 2, 2005·Toxicology and Applied Pharmacology·Geoffrey A CoddJames S Metcalf
Jul 30, 2005·Toxicon : Official Journal of the International Society on Toxinology·Rosário MartinsVitor M Vasconcelos
Apr 24, 2007·The Science of the Total Environment·Lars HåkansonJulia K Hytteborn
May 18, 2007·FEMS Microbiology Letters·Laurie L RichardsonPaul V Zimba
Aug 10, 2007·Toxicon : Official Journal of the International Society on Toxinology·Rosário MartinsVitor Vasconcelos
Apr 29, 2008·Current Opinion in Biotechnology·Leanne A Pearson, Brett A Neilan
Jun 26, 2009·Microbial Ecology·Miroslav GantarLaurie L Richardson

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Citations

Jan 29, 2013·Microbial Ecology·S M PowellM L Tamplin
Aug 8, 2013·Marine Drugs·Katerina VareliIoannis Sainis
Jul 3, 2013·Proceedings of the National Academy of Sciences of the United States of America·Javier Paz-YepesBrian Palenik
Mar 19, 2013·Bulletin of Environmental Contamination and Toxicology·Ralph Alquezar, Amie Anastasi
Mar 15, 2011·Toxicon : Official Journal of the International Society on Toxinology·Patrizia Pagliara, Carmela Caroppo
Mar 19, 2015·Journal of Toxicology and Environmental Health. Part a·Maria Sofia CostaRosário Martins
Jun 24, 2016·Marine Pollution Bulletin·Hugues LemonnierThierry Laugier
Jan 25, 2018·Toxins·Sylwia Śliwińska-WilczewskaAdam Latała
Oct 2, 2019·Environmental Microbiology·Maria J RomeuFilipe J M Mergulhão
Sep 7, 2017·Bulletin of Environmental Contamination and Toxicology·Xian-Ling XiangYi-Long Xi
Jun 3, 2017·Viruses·Ayalla Fedida, Debbie Lindell
Jul 13, 2020·The Science of the Total Environment·F K MammoS Kumari
Nov 26, 2019·Interdisciplinary Toxicology·Enver Ersoy AndedenBelma Aslim

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Methods Mentioned

BETA
PCR
scrapings

Software Mentioned

StatSoft
BLAST

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