Are liver nested stromal epithelial tumors always low aggressive?

World Journal of Gastroenterology : WJG
Tania MeletaniRossana Berardi

Abstract

Nested stromal-epithelial tumor (NSET) is a non-hepatocytic and non-biliary tumor of the liver consisting of nests of epithelial and spindled cells with associated myofibroblastic stroma and variable intra-lesional calcification and ossification, which represents a very rare and challenging disease. Most of the reported cases have been treated with surgery, obtaining a long survival outcome. Here, we report the case of a 31-year-old Caucasian man who underwent surgery at our institution for a large, lobulated, multinodular mass of the right hemi-liver. The histological exam confirmed the diagnosis of NSET. After 6 mo from surgery, a liver recurrence was described and a chemo-embolization was performed. After a further disease progression, based on the correlation between the histological features of the disease and those of the hepatoblastoma, a similar chemotherapy regimen (with cisplatin and ifosfamide/mesna chemotherapy, omitting doxorubicin due to liver impairment) was administered. However, infection of the biliary catheter required a dose modification of the treatment. No benefit was noted and a progression of disease was radiologically assessed after only four cycles. The worsening of the clinical status prevented furthe...Continue Reading

References

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Citations

Jul 11, 2021·Cirugia Española·María Pérez ReyesJulio Santoyo Santoyo
Sep 19, 2020·Cirugía española·María Pérez ReyesJulio Santoyo Santoyo

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Methods Mentioned

BETA
biopsy

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