Are monamine oxidase inhibitors in disposition to malignant hyperthermia contraindicated? Discussion based on a case report

Anästhesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS
F WapplerN Roewer

Abstract

We report on a young patient with a positive family history for malignant hyperthermia (MH), who was diagnosed as susceptible to MH in our malignant hyperthermia laboratory by the in vitro-contracture test. Prior to the investigation of MH-susceptibility, the patient had been on medication with moclobemide, a monoamine oxidase (MAO) inhibitor, over a period of 13 months for treatment of a hyperactivity disorder. During the therapy with moclobemide no signs of relevant side effects were observed. However, some authors regard MAO-inhibitors as MH-triggering agents. The risk of MH-patients due to the therapy with MAO-inhibitors and the association between MH and the neuroleptic malignant syndrome is discussed in this case report.

Citations

Dec 14, 1999·Anaesthesia·L S Koupparis

❮ Previous
Next ❯

Related Concepts

Related Feeds

Attention Disorders

Attention is involved in all cognitive activities, and attention disorders are reported in patients with various neurological diseases. Here are the latest discoveries pertaining to attention disorders.

Related Papers

The British Journal of Psychiatry : the Journal of Mental Science
F R SchneierM R Liebowitz
European Journal of Pediatric Surgery : Official Journal of Austrian Association of Pediatric Surgery ... [et Al] = Zeitschrift Für Kinderchirurgie
W UmmenhoferA Urwyler
© 2021 Meta ULC. All rights reserved