Are neonatal outcomes of triplet pregnancies different from those of singletons according to gestational age?

Journal of Perinatal Medicine
Georgios MitsiakosVassiliki Soubasi

Abstract

Multiple pregnancies sustain the high pace of extreme prematurity. Little evidence is available about triplet gestation given the evolution in their management during the last decades. The aim of the study was to compare the neonatal outcomes of triplets with those of matched singletons in a cohort study. An observational retrospective cohort study of triplets and matched singletons born between 2004 and 2017 matched by gestational age was conducted. Additionally, the investigation performed in regard to data from the overall Greek population of interest. The primary outcome was mortality or severe neonatal morbidity based on pregnancy type. A total of 237 triplets of 24-36 weeks' gestation and 482 matched singletons were included. No differences in the primary outcome between triplets and singletons were found. Rates of severe neonatal morbidities did not differ significantly between triplets and singletons. A threshold of 1000 gr for birthweight and 28 weeks' gestation for gestational age determined survival on triplets [OR: 0.08 (95% CI: 0.02-0.40, p=0.0020) and OR: 0.13 (95% CI: 0.03-0.57, p=0.0020) for gestational age and birthweight respectively]. In Greece stillbirths in triplets was 8 times higher than that of singleton...Continue Reading

References

Dec 24, 2002·Archives of Disease in Childhood. Fetal and Neonatal Edition·E S ShinwellB Reichman
Feb 21, 2003·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Praveen BallabhAlfred N Krauss
Mar 14, 2003·American Journal of Obstetrics and Gynecology·Alan H Jobe
Jul 13, 2005·Archives of Ophthalmology·UNKNOWN International Committee for the Classification of Retinopathy of Prematurity
Dec 7, 2011·Swiss Medical Weekly·Romaine Arlettaz MiethHans-Ulrich Bucher
Jan 15, 2013·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Mamoru MorikawaHisanori Minakami
May 1, 2015·Twin Research and Human Genetics : the Official Journal of the International Society for Twin Studies·Kristy M FennessyMark P Umstad
Mar 2, 2016·PloS One·Anna HeinoUNKNOWN Euro-Peristat Scientific Committee
May 21, 2016·Journal of Neonatal-perinatal Medicine·M Andrade RodriguesJ Maria de A Lopes
Sep 24, 2016·Obstetrics and Gynecology·UNKNOWN American College of Obstetricians and Gynecologists’ Committee on Practice Bulletins—Obstetrics
Mar 23, 2017·The Cochrane Database of Systematic Reviews·Devender RobertsStuart R Dalziel
Mar 20, 2018·The Journal of Pediatrics·Rosemary D HigginsTonse N K Raju
Apr 10, 2018·American Journal of Obstetrics and Gynecology·Alan H Jobe, Robert L Goldenberg
Nov 23, 2018·Pediatrics·Prakesh S ShahUNKNOWN International Network for Evaluation of Outcomes (iNEO) in Neonates Investigators
Dec 26, 2018·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·J CuradoA Khalil
Jul 25, 2019·Obstetrics & Gynecology Science·Kyu-Sang KyeongCheong-Rae Roh
Aug 14, 2019·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Joachim W DudenhausenUNKNOWN EPICE Research Group
Jan 31, 2020·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·S V GlinianaiaUNKNOWN NorSTAMP collaborators
Apr 25, 2020·American Journal of Perinatology·Donna S LambersMounira Habli
May 28, 2020·Obstetrics and Gynecology·Takafumi UshidaUNKNOWN Neonatal Research Network of Japan

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Pediatrics
Prakesh S ShahInternational Network for Evaluation of Outcomes (iNEO) in Neonates Investigators
Twin Research and Human Genetics : the Official Journal of the International Society for Twin Studies
Yoshie YokoyamaKarri Silventoinen
Journal of Clinical Ultrasound : JCU
T HataR M Hill
Science
J E Anderson
© 2021 Meta ULC. All rights reserved