Are people with negative diabetes screening tests falsely reassured? Parallel group cohort study embedded in the ADDITION (Cambridge) randomised controlled trial.

BMJ : British Medical Journal
Charlotte A M PaddisonSimon J Griffin

Abstract

To assess whether receiving a negative test result at primary care based stepwise diabetes screening results in false reassurance. Parallel group cohort study embedded in a randomised controlled trial. 15 practices (10 screening, 5 control) in the ADDITION (Cambridge) trial. 5334 adults (aged 40-69) in the top quarter for risk of having undiagnosed type 2 diabetes (964 controls and 4370 screening attenders). Perceived personal and comparative risk of diabetes, intentions for behavioural change, and self rated health measured after an initial random blood glucose test and at 3-6 and 12-15 months later (equivalent time points for controls). A linear mixed effects model with control for clustering by practice found no significant differences between controls and people who screened negative for diabetes in perceived personal risk, behavioural intentions, or self rated health after the first appointment or at 3-6 months or 12-15 months later. After the initial test, people who screened negative reported significantly (but slightly) lower perceived comparative risk (mean difference -0.16, 95% confidence interval -0.30 to -0.02; P=0.04) than the control group at the equivalent time point; no differences were evident at 3-6 and 12-15 ...Continue Reading

References

Jun 16, 1990·BMJ : British Medical Journal·S Kinlay, R F Heller
Dec 1, 1987·Family Practice·T Tymstra, B Bieleman
Jan 1, 1995·Diabetic Medicine : a Journal of the British Diabetic Association·D R WilliamsC R Palmer
Nov 26, 1999·Social Science & Medicine·C ShawT M Marteau
Jun 27, 2000·Diabetes/metabolism Research and Reviews·S J GriffinN J Wareham
Mar 7, 2001·BMJ : British Medical Journal·T M MarteauP Sasieni
Apr 20, 2001·BMJ : British Medical Journal·N J Wareham, S J Griffin
May 25, 2002·Diabetic Medicine : a Journal of the British Diabetic Association·M C AdriaanseR J Heine
Nov 25, 2003·Diabetic Medicine : a Journal of the British Diabetic Association·A J FarmerP M Salkovskis
Aug 20, 2004·Diabetic Medicine : a Journal of the British Diabetic Association·M C AdriaanseR J Heine
Nov 10, 2004·British Journal of Cancer·D P FrenchT M Marteau
Sep 6, 2005·Diabetes/metabolism Research and Reviews·Marcel C Adriaanse, Frank J Snoek
Sep 27, 2005·Psycho-oncology·David P FrenchTheresa M Marteau
Oct 26, 2005·Diabetic Medicine : a Journal of the British Diabetic Association·T C SkinnerK Khunti
Apr 23, 2008·BMJ : British Medical Journal·Elizabeth C Goyder
Apr 23, 2008·BMJ : British Medical Journal·Clare L GilliesKamlesh Khunti
Jul 18, 2008·Journal of Clinical Epidemiology·David P FrenchStephen Sutton

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Citations

Apr 25, 2012·Diabetologia·P T Sawicki
May 21, 2013·BMC Public Health·Miranda WijdenesDanielle R M Timmermans
Jul 3, 2013·Annals of Behavioral Medicine : a Publication of the Society of Behavioral Medicine·Julie I WillemsHarry J de Koning
Sep 2, 2011·Journal of General Internal Medicine·Nicolas RodondiJacques Cornuz
Jun 21, 2014·Diabetes Research and Clinical Practice·Yuka TsujimuraTakeo Nakayama
Jul 16, 2011·Diabetes, Metabolic Syndrome and Obesity : Targets and Therapy·Pascal BovetIsabelle Hagon-Traub
Oct 6, 2010·Diabetes, Obesity & Metabolism·R K SimmonsS J Griffin
Oct 29, 2011·Health Expectations : an International Journal of Public Participation in Health Care and Health Policy·Martine H P IckenrothTrudy van der Weijden
Feb 11, 2014·British Journal of Health Psychology·Kati VähäsarjaMarita Poskiparta
Nov 30, 2010·Research in Social & Administrative Pharmacy : RSAP·Egbert J F LambertsRolf P van Hulten
Jan 25, 2014·Clinical Trials : Journal of the Society for Clinical Trials·Justin B Echouffo-Tcheugui, Philip C Prorok
Jun 1, 2011·Epidemiologic Reviews·Justin B Echouffo-TcheuguiK M Venkat Narayan
Sep 13, 2017·British Journal of Health Psychology·Grace C CooperDavid P French
May 8, 2018·British Journal of Cancer·David P FrenchLouise S Donnelly

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