Are PROMs used adequately in sports research? An analysis of 54 randomized controlled trials with PROMs as endpoint.

Scandinavian Journal of Medicine & Science in Sports
Jonas JensenMichael R Krogsgaard

Abstract

Deviations from adequate use and reporting of PROMs may be problematic and misleading. The aim of this study was to investigate the extent of such problems in randomized clinical trials (RCTs). RCTs involving sports medicine research that used PROMs as primary outcomes were identified in 13 preselected journals. The articles were reviewed for nine potential problems related to how the PROM was used and how the data had been reported. The potential problems were as follows: aggregating subscale scores; combining patient-reported scores with physical, clinical, or para-clinical measures; using a PROM to diagnose or evaluate the individual patient; using a PROM for one leg or arm; selectively excluding domains or items; constructing a PROM for the specific occasion; mixing PROM formats (ie, digital, paper, telephone, e-mail, in person); ambiguous instructions for how the PROM should be completed; and recall bias. As covariates, we registered journal impact factor, year of publication, and existence of a registered protocol. In 29 (53.7%) of 54 identified RCTs, at least one potential problem was identified, the most common being aggregation of domain scores. This was not different with a published protocol or dependent on journal r...Continue Reading

References

Jan 26, 2008·Journal of Shoulder and Elbow Surgery·Christopher R ConstantPascal Boileau
Mar 25, 2008·The American Journal of Sports Medicine·Timothy P C KaneJames D F Calder
Feb 17, 2009·Lancet·S E LambUNKNOWN Collaborative Ankle Support Trial (CAST Group)
Jan 12, 2010·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·Erhan BasadJürgen Steinmeyer
Jul 28, 2010·The New England Journal of Medicine·Richard B FrobellL Stefan Lohmander
Nov 3, 2010·Annals of Internal Medicine·Kelli D AllenHayden B Bosworth
Nov 5, 2010·The New England Journal of Medicine·Samuel K Van de Velde, Thomas J Gill
Nov 5, 2010·The New England Journal of Medicine·Jonathan CominsMichael Krogsgaard
Jan 27, 2011·The Journal of Bone and Joint Surgery. American Volume·Nina ShervinHenrik Malchau
Mar 2, 2011·British Journal of Sports Medicine·Jyrki A KettunenUrho M Kujala
Jan 26, 2013·BMJ : British Medical Journal·Richard B FrobellL Stefan Lohmander
Feb 1, 2014·The American Journal of Sports Medicine·Jason L DragooKevin T Nead
Apr 10, 2014·The American Journal of Sports Medicine·Daniel SarisUNKNOWN SUMMIT study group
May 23, 2014·JAMA : the Journal of the American Medical Association·Kim L BennellRachelle Buchbinder
Jun 28, 2014·British Journal of Sports Medicine·Hanna C Björnsson HallgrenLars E Adolfsson
Jul 26, 2014·BMJ : British Medical Journal·Damian GriffinUNKNOWN UK Heel Fracture Trial Investigators
Feb 26, 2015·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·Sheila McRaePeter MacDonald
Mar 11, 2015·JAMA : the Journal of the American Medical Association·Amar RanganUNKNOWN PROFHER Trial Collaborators
Feb 10, 2016·Annals of Internal Medicine·Raine SihvonenUNKNOWN Finnish Degenerative Meniscal Lesion Study Group
Jun 17, 2016·The American Journal of Sports Medicine·Iikka LanttoJuhana Leppilahti
Jan 24, 2017·Arthroscopy : the Journal of Arthroscopic & Related Surgery : Official Publication of the Arthroscopy Association of North America and the International Arthroscopy Association·Augustus D MazzoccaMark P Cote
May 17, 2017·JAMA : the Journal of the American Medical Association·Timothy E McAlindonRobert J Ward
Sep 16, 2017·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·Elizaveta KonMaurilio Marcacci
Dec 21, 2017·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·L B MokkinkC B Terwee

❮ Previous
Next ❯

Citations

Jan 20, 2021·Scandinavian Journal of Medicine & Science in Sports·Christian F HansenMichael R Krogsgaard
Apr 28, 2021·Scandinavian Journal of Medicine & Science in Sports·Stephen D R Harridge

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Scandinavian Journal of Medicine & Science in Sports
Christian Fugl HansenMichael R Krogsgaard
Scandinavian Journal of Medicine & Science in Sports
Michael R KrogsgaardJonathan D Comins
© 2021 Meta ULC. All rights reserved