Are Q(ST)-F(ST) comparisons for natural populations meaningful?

Molecular Ecology
B PujolJ R Pannell

Abstract

Comparisons between putatively neutral genetic differentiation amongst populations, F(ST), and quantitative genetic variation, Q(ST), are increasingly being used to test for natural selection. However, we find that approximately half of the comparisons that use only data from wild populations confound phenotypic and genetic variation. We urge the use of a clear distinction between narrow-sense Q(ST), which can be meaningfully compared with F(ST), and phenotypic divergence measured between populations, P(ST), which is inadequate for comparisons in the wild. We also point out that an unbiased estimate of Q(ST) can be found using the so-called 'animal model' of quantitative genetics.

References

Sep 3, 2004·Evolution; International Journal of Organic Evolution·Emmanuelle PorcherClaire Lavigne
Jul 30, 2005·Evolution; International Journal of Organic Evolution·Jon E BrommerLars Gustafsson
May 17, 2006·Trends in Ecology & Evolution·Massimo Pigliucci
Nov 9, 2006·Evolution; International Journal of Organic Evolution·Anna M WójcikJan M Wójcik
Feb 20, 2007·Journal of Evolutionary Biology·J D HadfieldI P F Owens
Jun 23, 2007·Journal of Evolutionary Biology·J R St Juliana, F J Janzen
Aug 9, 2007·Evolution; International Journal of Organic Evolution·Fanie PelletierMarco Festa-Bianchet
Nov 22, 2007·Journal of Evolutionary Biology·T LeinonenJ Merilä
Mar 28, 2008·Molecular Ecology·Michael C Whitlock
May 6, 2008·PLoS Genetics·William G HillPeter M Visscher
Aug 1, 1996·Evolution; International Journal of Organic Evolution·Derek A Roff

❮ Previous
Next ❯

Citations

Oct 15, 2010·Proceedings. Biological Sciences·Brooks E Miner, Benjamin Kerr
Jun 7, 2014·Annual Review of Phytopathology·Silvia RestrepoDaniel R Matute
Dec 9, 2015·PeerJ·Guillermo CastilloJuan Núñez-Farfán
Apr 5, 2011·Journal of Evolutionary Biology·J E Brommer
Jan 25, 2012·Molecular Ecology·Michael M HansenUNKNOWN GeM Working Group
Nov 1, 2012·Molecular Ecology·Jean-Baptiste LamySylvain Delzon
Dec 4, 2014·Evolutionary Applications·Catalina Monzón-ArgüelloCarlos Garcia de Leaniz
Feb 13, 2010·Evolution; International Journal of Organic Evolution·Sylvain AntoniazzaAlexandre Roulin
Oct 12, 2013·The New Phytologist·John R Pannell, Peter D Fields
Feb 14, 2015·Studies in History and Philosophy of Biological and Biomedical Sciences·Michael D Edge, Noah A Rosenberg
Nov 26, 2015·PloS One·Ilga PorthYousry A El-Kassaby
Jul 27, 2017·Heredity·M Schmid, F Guillaume
Mar 3, 2012·Evolution; International Journal of Organic Evolution·Sandra HangartnerKatja Räsänen
Aug 16, 2016·American Journal of Botany·Andrea E BerardiDouglas R Taylor
Feb 1, 2019·Journal of Evolutionary Biology·Emilien LuquetAnssi Laurila

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.