PMID: 11899180Mar 20, 2002Paper

Are stentless valves hemodynamically superior to stented valves? A prospective randomized trial

The Annals of Thoracic Surgery
Gideon N CohenB S Goldman

Abstract

Although stentless aortic bioprostheses are believed to offer improved outcomes, hemodynamic benefits remain unsubstantiated. Fifty-three patients were randomized to receive the stented C-E pericardial valve (CE) and 46 patients the Toronto Stentless Porcine valve (SPV). Annuli were sized for the optimal insertion of both valve types, such that surgeons were required to commit to specific valve sizes before randomization. Echocardiographic measurements and functional status (Duke Activity Status Index) were assessed at 3 and 12 months postoperatively. Although cardiopulmonary bypass times (CE: 118.6+/-36.3 minutes; SPV: 148.5+/-30.9 minutes; p = 0.0001) and aortic cross-clamp times (CE: 95.4+/-28.6 minutes; SPV: 123.6+/-24.1 minutes; p = 0.0001) were significantly prolonged in the SPV group, perioperative morbidity and mortality was similar between groups. Neither valve offered a superior internal diameter for any given annular diameter (mean decrease in left ventricular outflow tract diameter after valvular implantation: SPV: 3.4+/-1.11 mm versus CE: 3.7+/-1.33 mm; p = 0.25). Although labeled mean valve size was significantly larger in the SPV group, the actual mean valve size based on internal valvular diameter was no differe...Continue Reading

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Citations

Jul 8, 2008·Journal of Artificial Organs : the Official Journal of the Japanese Society for Artificial Organs·Shigehiko Tokunaga, Ryuji Tominaga
Jun 18, 2010·Journal of Artificial Organs : the Official Journal of the Japanese Society for Artificial Organs·Shigehiko Tokunaga, Ryuji Tominaga
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