PMID: 2507450Aug 1, 1989Paper

Are the mast cells antigen presenting cells?

Immunological Investigations
K BanovacA Rabinovitch

Abstract

Mast cells have an important role in allergic reactions secreting histamine and other mediators of immediate hypersensitivity. In the present study we evaluated major histocompatibility complex (MHC) class II antigen expression in mast cells and their possible role in antigen presentation. In rats, 10% of mast cells isolated from the pleural cavity expressed MHC class II antigen; after incubation with gamma interferon (INF) 80% of the cells were positive. These findings suggest that mast cells, in addition to their secretory function in allergic reactions, may also function as antigen presenting cells.

References

May 20, 1987·Journal of Immunological Methods·A Reshef, D W MacGlashan
Oct 8, 1987·The New England Journal of Medicine·C A Dinarello, J W Mier
Dec 1, 1987·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·C Y LiO Lazcano-Villareal
Jun 12, 1981·Science·B Benacerraf
Nov 1, 1984·Transplantation·R AlejandroD H Mintz
Sep 1, 1983·Veterinary Pathology·J R WrightP Thibert

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Citations

May 15, 2010·Veterinary Research Communications·Ulker ErenOzay Gules
Jan 24, 1998·Journal of Dermatological Science·J GrabbeB M Henz
Jan 1, 1991·The British Journal of Dermatology·A Kobza BlackR J Pye
Jun 5, 2007·Immunobiology·Erietta StelekatiSilvia Bulfone-Paus
Jun 20, 2006·Veterinary Immunology and Immunopathology·Tzu-yin LinCheryl A London
Oct 13, 2009·Immunity·Erietta StelekatiSilvia Bulfone-Paus
Jan 1, 1995·International Reviews of Immunology·B L Gruber
Jan 27, 2019·The Journal of Immunology : Official Journal of the American Association of Immunologists·Eva KritikouIlze Bot
Mar 2, 2019·Journal of Immunotoxicology·Hillary L ShaneStacey E Anderson
Feb 13, 2001·Experimental Dermatology·B M HenzM Babina
Jan 1, 1995·International Journal of Dermatology·S WeberB M Czarnetzki
Nov 24, 2004·The Journal of Immunology : Official Journal of the American Association of Immunologists·Martin J HessnerSoumitra Ghosh
Jul 1, 1992·Infection and Immunity·J KomisarJ Tseng
Jul 1, 1994·Clinics in Dermatology·B L Gruber

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