Are the precapillary sphincters and metarterioles universal components of the microcirculation? An historical review

The Journal of Physiological Sciences : JPS
Tatsuo Sakai, Yasue Hosoyamada

Abstract

The microcirculation is a major topic in current physiology textbooks and is frequently explained with schematics including the precapillary sphincters and metarterioles. We re-evaluated the validity and applicability of the concepts precapillary sphincters and metarterioles by reviewing the historical context in which they were developed in physiology textbooks. The studies by Zweifach up until the 1950s revealed the unique features of the mesenteric microcirculation, illustrated with impressive schematics of the microcirculation with metarterioles and precapillary sphincters. Fulton, Guyton and other authors introduced or mimicked these schematics in their physiology textbooks as representative of the microcirculation in general. However, morphological and physiological studies have revealed that the microcirculation in the other organs and tissues contains no metarterioles or precapillary sphincters. The metarterioles and precapillary sphincters were not universal components of the microcirculation in general, but unique features of the mesenteric microcirculation.

References

Jul 1, 1979·Archivum Histologicum Japonicum = Nihon Soshikigaku Kiroku·M MurakamiK Nakamura
Apr 1, 1977·The American Journal of Cardiology·L SherfH N Neufeld
May 1, 1977·Stroke; a Journal of Cerebral Circulation·T ItakuraN Shimizu
Jul 1, 1976·Microvascular Research·M P WiedemanH N Mayrovitz
Jan 1, 1987·Journal of Cardiovascular Pharmacology·D Gustafsson
Jan 1, 1988·Journal of Clinical Gastroenterology·M OdaM Tsuchiya
Feb 14, 1986·The American Journal of Medicine·F M Sacks, V J Dzau
Jan 1, 1988·Journal of Clinical Gastroenterology·M KitajimaA Oshima
May 1, 1987·Archives of Ophthalmology·S Yoneya, M O Tso
Feb 1, 1985·Pflügers Archiv : European journal of physiology·P R Saxena, P D Verdouw
Oct 1, 1971·Microvascular Research·R S McCuskey
Apr 1, 1967·Journal of Ultrastructure Research·J A Rhodin
Jan 1, 1968·Zeitschrift für Zellforschung und mikroskopische Anatomie·E A Schenk, A el-Badawi
Jun 1, 1969·The American Journal of Physiology·J P Delaney
Oct 12, 1965·Zeitschrift für Zellforschung und mikroskopische Anatomie·K A Norberg, L Olson
Sep 1, 1981·Acta Physiologica Scandinavica·J Hillman, J Lundvall
Feb 1, 1983·The Anatomical Record·J A Holley, M A Fahim
Apr 1, 1983·The Anatomical Record·B P LaneE Drummond
Feb 1, 1981·The British Journal of Dermatology·J C Higgins, R A Eady
Jun 1, 1980·The American Journal of Anatomy·B G Anderson, W D Anderson
Jun 25, 1995·Journal of the Autonomic Nervous System·A L KrogstadB G Wallin
Jun 1, 1995·Anatomy and Embryology·S SasakiT Sakai
May 1, 1993·Journal of the Autonomic Nervous System·R Mann, C Bell
Nov 5, 1997·Microcirculation : the Official Journal of the Microcirculatory Society, Inc·I M Braverman
Jan 26, 2002·Microscopy Research and Technique·Tadahiko Iijima, Jing-Qi Zhang

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Citations

Feb 6, 2016·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·A J DemetrisD B Stolz
May 17, 2018·Journal of Neurophysiology·Sarah E V Richards, Stephen D Van Hooser
Aug 19, 2018·Microcirculation : the Official Journal of the Microcirculatory Society, Inc·Daniel M HiraiDavid C Poole
Nov 27, 2018·Analytical Sciences : the International Journal of the Japan Society for Analytical Chemistry·Kae SatoAya Furuta
Oct 18, 2015·American Journal of Physiology. Heart and Circulatory Physiology·Graham Mathew FraserCraig Douglas Steinback
Feb 1, 2020·Nature Communications·Jung Bok LeeHak-Joon Sung
Jan 22, 2020·Nature Communications·Søren GrubbMartin Lauritzen

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Methods Mentioned

BETA
electron microscopy
transmission electron microscopy
scanning electron microscopy

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