Are treatment supporters relevant in long-term Antiretroviral Therapy (ART) adherence? Experiences from a long-term ART cohort in Uganda.

Global Public Health
S NakamanyaJanet Seeley

Abstract

This study aimed to understand the relevance of treatment supporters in adherence among people living with HIV taking Anti-retroviral therapy (ART) for more than five years in Uganda. In-depth interviews were conducted with 50 participants (28 women and 22 men) of the Complications of Long-Term ART (CoLTART) cohort with experience of at least five years on ART in Uganda. Participants were stratified by line of ART regimen and viral loads of less or above 1000 copies/ml. Data were analyzed thematically. Many participants felt that a treatment supporter was most useful at the beginning of therapy before individuals get used to the drugs or when they are still weak. However, this did not reflect treatment outcomes, as many individuals without treatment supporters had failed on first line ART regimens and were switched to second line ART. Those who were still on first line had viral loads of ≥1000 copies/ml. There was a preference for female treatment supporters, many of who were persistent in their supportive role. Treatment supporters remain important in adherence to long-term ART. HIV-care providers need to encourage the involvement of a treatment supporter for individuals taking ART long-term.

References

Nov 23, 2006·BMC Public Health·Charles A S KaramagiKristian Heggenhougen
Nov 30, 2006·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Jean B NachegaGary Maartens
Oct 25, 2007·Tropical Medicine & International Health : TM & IH·Jean-François EtardUNKNOWN ANRS 1215/1290 Study Group
Jan 30, 2009·PLoS Medicine·Norma C WareDavid R Bangsberg
Dec 2, 2009·Qualitative Health Research·Amy M MedleyMichael D Sweat
Feb 25, 2011·AIDS Care·Annelie K GusdalUNKNOWN INRUD-IAA project
Sep 29, 2011·AIDS and Behavior·Kelli N O'LaughlinNorma C Ware
Jul 4, 2013·Journal of the International AIDS Society·Gottfried HirnschallAndrew Ball
Feb 11, 2014·The Journal of the Association of Nurses in AIDS Care : JANAC·J Daniel KellyThomas P Giordano
Oct 12, 2014·Current HIV/AIDS Reports·Reuben N RobbinsRobert H Remien
May 8, 2015·Global Public Health·Enid Schatz, Janet Seeley
Jul 15, 2015·Bulletin of the World Health Organization·Kathryn ChurchBasia Zaba
Dec 4, 2016·Journal of the International AIDS Society·Steve KantersEdward J Mills
May 10, 2017·The Lancet. HIV·Jemma O'ConnorUNKNOWN UK Collaborative HIV Cohort (CHIC) Study
May 10, 2017·AIDS Research and Therapy·Billy Nsubuga MayanjaUNKNOWN CoLTART study team

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Citations

Aug 5, 2020·AIDS Education and Prevention : Official Publication of the International Society for AIDS Education·Christopher TumwineStephen Bell
Dec 15, 2020·HIV/AIDS : Research and Palliative Care·Habtamu AreriGillian Harvey
Jul 14, 2021·Global Public Health·Relebohile Morojele

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