Are vaccine strain, type or administration protocol risk factors for canine parvovirus vaccine failure?

Veterinary Microbiology
K D AltmanM P Ward

Abstract

Canine parvovirus (CPV) is a highly contagious and worldwide cause of serious and often fatal disease in dogs, despite the widespread availability of vaccines. Which vaccine-related factors are associated with vaccination failure is largely unknown, and there are no reports from Australia. In this study - the first national population-level CPV study of its kind ever conducted - we analysed data on 594 cases of apparent CPV vaccination failure reported from an Australian national surveillance system to determine whether vaccine strain, type or administration protocol are risk factors for vaccination failures. The strain of CPV used in vaccine manufacture was not significantly associated with vaccination failure in clinical practice. The vaccine type (killed versus attenuated vaccine) for puppies diagnosed with CPV was associated with a lower mean age at time of vaccination (P=0.0495). The age at administration of the last CPV vaccination a puppy received prior to presenting with disease was a significant (P=0.0334) risk factor for vaccination failure, irrespective of whether the vaccine was marketed for a 10-week or 12-week or greater vaccination finish protocol. There was also a strong negative correlation between age at last ...Continue Reading

Citations

Aug 26, 2020·Australian Veterinary Journal·M W KimL N Twomey
Sep 10, 2020·Viruses·Hiu Ying Esther YipFarhid Hemmatzadeh
Aug 6, 2020·Australian Veterinary Journal·M KelmanM P Ward
Apr 27, 2021·Tierärztliche Praxis. Ausgabe K, Kleintiere/Heimtiere·Michèle BergmannKatrin Hartmann
Jun 5, 2021·Veterinary World·F M Yasir HasibSharmin Chowdhury
Jul 12, 2021·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Matthew Terzungwe TionGregory Anatoliiovych Zon
Aug 29, 2021·Pathogens·Monia CocchiPaola De Benedictis

❮ Previous
Next ❯

Related Concepts

Related Feeds

Acute Disseminated Encephalomyelitis

Acute disseminated encephalomyelitis (ADEM) is a rare inflammatory demyelinating disease of the central nervous system. Discover the latest research on acute disseminated encephalomyelitis here.