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Are we approaching the post-blockbuster era? Pharmacodiagnostics and rational drug development

Expert Review of Molecular Diagnostics

Nov 13, 2008

Jan Trøst Jørgensen

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PubMed

Abstract

In the future, it may be a pharmacodiagnostic test that decides which drug to choose for the individual patient and, to a much lesser extent, the average results from large randomized clinical trials or the marketing efforts of the pharmaceutical companies. Personalized medicine or stra...read more

Mentioned in this Paper

Drug Development
Combinatorial Chemistry Techniques
Clinical Trials, Randomized
Menopause
Clinical Pharmacology Discipline
Molecular Diagnostic Techniques
Drug Modeling
Paper Details
References
  • References7
  • Citations8
1
  • References7
  • Citations8
1

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Are we approaching the post-blockbuster era? Pharmacodiagnostics and rational drug development

Expert Review of Molecular Diagnostics

Nov 13, 2008

Jan Trøst Jørgensen

PMID: 18999921

DOI: 10.1586/14737159.8.6.689

Abstract

In the future, it may be a pharmacodiagnostic test that decides which drug to choose for the individual patient and, to a much lesser extent, the average results from large randomized clinical trials or the marketing efforts of the pharmaceutical companies. Personalized medicine or stra...read more

Mentioned in this Paper

Drug Development
Combinatorial Chemistry Techniques
Clinical Trials, Randomized
Menopause
Clinical Pharmacology Discipline
Molecular Diagnostic Techniques
Drug Modeling

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Human Vascular Endothelial Cell Atlas: Young & Old

Examining the genomics, transcriptomics, proteomics and metabolomics of the human vascular endothelial cells at the single cell level will help build a single cell atlas of human vascular endothelium, which would give a unique ID card for each cell type, a three-dimensional map of how cell types work together to form tissues and insights into how changes in the map underlie health and disease of the vascular endothelium from young to old age. Disocver the latest research on the single cell atlas of human vascular endothelial cell atlas here.

Related Papers

Nature Reviews. Drug Discovery

Stratified medicine: strategic and economic implications of combining drugs and clinical biomarkers

Nature Reviews. Drug DiscoveryMarch 24, 2007
Mark R TrusheimFrank L Douglas
Paper Details
References
  • References7
  • Citations8
1
  • References7
  • Citations8
1

Download from

Publisher
PubMed
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