Are We Improving Erectile Function Recovery After Radical Prostatectomy? Analysis of Patients Treated over the Last Decade

European Urology
Paolo CapogrossoJohn P Mulhall

Abstract

The last decade has seen several advances in radical prostatectomy (RP) technique and post-RP care that are relevant to erectile function (EF) recovery. We examined whether these practice changes have led to observed improvements in EF rates over time. We identified 2364 patients treated with either open or minimally-invasive RP at a single academic center in 2008-2015. To mitigate confounding by the surgical learning curve, only patients treated by surgeons who performed at least 100 procedures were considered. EF before and after RP was assessed by the International Index of Erectile Function 6 (IIEF-6), with recovery defined as IIEF-6 ≥24. We analyzed EF recovery rates of patients treated with bilateral nerve-sparing surgery and free from adjuvant/salvage treatment at the time of EF assessment. Local polynomial regression analyses explored changes in the outcomes over time. Linear and logistic regression analyses were used to estimate the influence of year of surgery on baseline variables and EF recovery. We observed a significant decrease over time of the EF recovery rates at both 12 and 24mo post-RP (all p=0.01). However, patient's age at surgery increased over time (mean increase of 0.5 per year; p<0.01), with a resultant...Continue Reading

Citations

Dec 15, 2019·International Journal of Impotence Research·Catherine E LovegroveSuks Minhas
Feb 20, 2020·Archives of Sexual Behavior·Lauren M Walker, Pablo Santos-Iglesias
Feb 23, 2020·Nature Reviews. Urology·Anthony J Costello
Aug 11, 2020·The World Journal of Men's Health·Koichi OkadaNorio Nonomura
Jan 29, 2021·International Journal of Urology : Official Journal of the Japanese Urological Association·Nobuhiro HagaHirofumi Matsuoka
Apr 24, 2021·BJU International·Paul CathcartMark Emberton
Jun 15, 2021·Frontiers in Surgery·Claudia KeschGiorgio Gandaglia
Jul 6, 2021·Sexual Medicine Reviews·Irene E JuManish I Patel
Oct 7, 2021·International Journal of Impotence Research·Fabio CastiglioneUNKNOWN Trauma and Reconstructive Urology Working Party of the European Association of Urology (EAU) Young Academic Urologists (YAU)

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