Are women who are treated for hypothyroidism at risk for pregnancy complications?

American Journal of Obstetrics and Gynecology
Tina O TanAaron B Caughey

Abstract

The purpose of this study was to investigate the outcomes that are associated with pregnancy and treated hypothyroidism. This was a retrospective cohort study of all women who received prenatal care and were delivered at the University of California, San Francisco, between 1989 and 2001. All patients with hypothyroidism diagnosed before pregnancy or early in pregnancy were identified. Maternal, fetal, and obstetric outcomes were then collected and analyzed for women with hypothyroidism and compared with women without hypothyroidism. Among 20,499 deliveries, there were 419 women (2.1%) who were treated for hypothyroidism during the study period. Hypothyroidism was more common among women > or =35 years old, white women, and women without Medicaid insurance. Treated hypothyroidism was not associated with any increase in maternal, fetal, or neonatal complications. In addition, hypothyroidism did not affect mode of delivery. Compared with patients without hypothyroidism, patients with treated hypothyroidism are not at any increased risk for perinatal morbidity.

References

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Citations

Aug 8, 2014·Obstetrical & Gynecological Survey·Phillip E PattonAaron B Caughey
Nov 26, 2011·Best Practice & Research. Clinical Endocrinology & Metabolism·Roberto Negro, Jorge Hector Mestman
Feb 9, 2008·Nursing & Health Sciences·Evy LidellCathrine Hildingh
Dec 8, 2010·Paediatric and Perinatal Epidemiology·William A GrobmanUNKNOWN Eunice Kennedy Shriver National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network
May 31, 2015·Journal of Reproductive Immunology·Ozlem Turhan IyidirGoksun Ayvaz
Dec 17, 2008·American Journal of Obstetrics and Gynecology·Anne L DunlopMona R Prasad
Dec 24, 2018·Acta Obstetricia Et Gynecologica Scandinavica·Griffith A BellJames L Mills
Jan 18, 2014·Endocrine Reviews·Bernadette Biondi, Leonard Wartofsky
Sep 28, 2012·The Journal of Clinical Endocrinology and Metabolism·Polyxeni KarakostaLeda Chatzi
Jun 25, 2010·Endocrine Reviews·G E KrassasD Glinoer
Aug 8, 2012·The Journal of Clinical Endocrinology and Metabolism·Leslie De GrootScott Sullivan
Jul 19, 2020·Journal of Clinical Medicine·Anna Karen Gárate-EscamillaAmir Hajjam El Hassani
Apr 28, 2018·Obstetrical & Gynecological Survey·Danielle Rosani ShinoharaIzabel Galhardo Demarchi
May 1, 2008·Endocrinología y nutrición : órgano de la Sociedad Española de Endocrinología y Nutrición·José Ignacio Jaén DíazCristina Martín Dal Gesso

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